by Faran Khalid, Hans Rosenberg, Ian Stiell | Nov 3, 2025 | Full Article, Journal Club, Neurology
Methodology: 3.5/5 Usefulness: 3.5/5 Alexandrov AW, et al. JAMA Neurol. 2025 Sep 1;82(9):905-914. doi: 10.1001/jamaneurol.2025.2253. Question and Methods: Authors aimed to determine if 0° head positioning reduces neurological deterioration and mortality in stroke...
by Kaitlin Endres, Hans Rosenberg, Ian Stiell | Oct 22, 2025 | Journal Club, Neurology
Methodology: 4.5/5 Usefulness: 4/5 Miao Z, et al. JAMA. 2025 Aug 19;334(7):582-591. doi: 10.1001/jama.2025.10800. Question and Methods: To compare clinical outcomes in patients with acute LVO for those who received intra-arterial tenecteplase after successful...
by Sandrine Pageau, Hans Rosenberg, Krishan Yadav | Apr 14, 2025 | Featured, Journal Club, Neurology
Methodology: 5/5 Usefulness: 4/5 Goyal M, et al. N Engl J Med. 2025 Feb 5. doi: 10.1056/NEJMoa2411668. Question and Methods: This multi-center, open label RCT of 530 patients presenting with medium-sized vessel stroke within 12h of last seen well compared functional...
by Josee Malette, Hans Rosenberg, Venkatesh Thiruganasambandamoorthy | May 20, 2024 | Full Article, Journal Club, Neurology
Methodology: 3/5 Usefulness: 2/5 Fischer U, et al. N Engl J Med. 2023 Jun 29;388(26):2411-2421. Question and Methods: RCT at 103 sites to compare outcomes at 30 days for early versus late DOAC initiation among patients with ischemic stroke and atrial fibrillation....
by Maria Berliant, Hans Rosenberg, Christian Vaillancourt | May 6, 2024 | Featured, Full Article, Journal Club, Neurology
Methodology: 4/5 Usefulness: 3/5 Zi W, et al. N Engl J Med. 2023 Jun 1;388(22):2025-2036. Editorial: Expanding Treatment for Acute Ischemic Stroke beyond Revascularization. Question and Methods: This multi-centre, triple-blind, double dummy RCT in China aimed to...
