Review of the formative literature of our current tPA time window in Acute Ischemic Stroke  After numerous case series and smaller prospective studies suggesting benefit for thrombolytic therapy (tPA), the early 90s ushered in the era of thrombolytic RCTs for acute ischemic stroke. Below, you will find a comprehensive review of these trials, and their … Continue reading Thrombolytic Therapy: A Stroke of Luck? Part 1