Journal Club Summary
Methodology Score: 3.5/5
Usefulness Score: 3 /5
Seymour CW, et al.
JAMA. 2016 Feb 23;315(8):762-74
Editorial: New Definitions for Sepsis and Septic Shock Continuing Evolution but With Much Still to Be Done
Abraham E.
JAMA. 2016;315(8):757-759
http://jama.jamanetwork.com/article.aspx?articleid=2492856
This is a retrospective cohort study that looked to validate the use current sepsis scores (SOFA, SIRS, LODS) as clinical criteria for sepsis, and to derive and validate a new, simple clinical score, qSOFA which includes RR, BP and GCS, that can be calculated with information that can be gathered quickly at the bedside. They were able to collect a large amount of encounters encompassing different types of population adding to the robustness of the derivation and validation. However, it was only validated retrospectively and not prospectively. Currently, the Sepsis-3 guideline, including qSOFA, is not endorses by SAEM or ACEP, given emergency physicians were not involved in the task force.
By: Dr. Isabelle Miles
This is a retrospective cohort study that looked to validate the use current sepsis scores (SOFA, SIRS, LODS) as clinical criteria for sepsis, and to derive and validate a new, simple clinical score, qSOFA which includes RR, BP and GCS, that can be calculated with information that can be gathered quickly at the bedside. They were able to collect a large amount of encounters encompassing different types of population adding to the robustness of the derivation and validation. However, it was only validated retrospectively and not prospectively. Currently, the Sepsis-3 guideline, including qSOFA, is not endorses by SAEM or ACEP, given emergency physicians were not involved in the task force.
By: Dr. Isabelle Miles
Epi lesson:
When describing the validity of measurement tools, various terms are commonly used:
Construct validity (which is of main concern), refers to how well a test measures what it claims to measure.
Criterion validity refers to the extent with which a test can predict an outcome now or in the future. Content validity refers to the extent to which a measure represents all facets of a given construct. Face validity is the extent to which a test is subjectively viewed by stakeholders as measuring the construct it claims to measure.
