Ketamine Compared With Morphine for Out-of-Hospital Analgesia for Patients With Traumatic Pain: A Randomized Clinical Trial

Ketamine Compared With Morphine for Out-of-Hospital Analgesia for Patients With Traumatic Pain: A Randomized Clinical Trial

Methodology: 3/5 Usefulness: 1.5/5 Le Cornec C, e al. JAMA Netw Open. 2024 Jan 2;7(1):e2352844.  Question and Methods: This was a multicenter, single-blind, noninferiority RCT, to assess the noninferiority of intravenous ketamine vs intravenous morphine for pain...
Effect of Bougie Use on First-Attempt Success in Tracheal Intubations: A Systematic Review and Meta-Analysis

Effect of Bougie Use on First-Attempt Success in Tracheal Intubations: A Systematic Review and Meta-Analysis

Methodology: 4/5 Usefulness: 3/5 von Hellmann R, et al. Ann Emerg Med. 2024 Feb;83(2):132-144.  Question and Methods: Systematic review of 18 studies (12 RCT) of adult patients comparing bougie use vs standard of care in tracheal intubations to evaluate first-attempt...
Peri-Intubation Hypoxia After Delayed Versus Rapid Sequence Intubation in Critically Injured Patients on Arrival to Trauma Triage: A Randomized Controlled Trial

Peri-Intubation Hypoxia After Delayed Versus Rapid Sequence Intubation in Critically Injured Patients on Arrival to Trauma Triage: A Randomized Controlled Trial

Methodology: 3/5 Usefulness: 3/5 Bandyopadhyay A, et al. Anesth Analg. 2023 May 1;136(5):913-919. Question and Methods: This is the first RCT looking at DSI vs RSI in adult trauma patients with no difficult airway features. All intubations performed by an anesthesia...
Effect of Noninvasive Airway Management of Comatose Patients With Acute Poisoning: A Randomized Clinical Trial

Effect of Noninvasive Airway Management of Comatose Patients With Acute Poisoning: A Randomized Clinical Trial

Methodology: 3.5/5 Usefulness: 3/5 Freund Y, et al. JAMA. 2023 Dec 19;330(23):2267-2274.  Question and Methods: Multicenter RCT involving comatose patients with suspected acute poisoning and GCS <9 compared a conservative airway strategy of withholding intubation...
Expedited transfer to a cardiac arrest centre for non-ST-elevation out-of-hospital cardiac arrest (ARREST): a UK prospective, multicentre, parallel, randomised clinical trial

Expedited transfer to a cardiac arrest centre for non-ST-elevation out-of-hospital cardiac arrest (ARREST): a UK prospective, multicentre, parallel, randomised clinical trial

Methodology: 5/5 Usefulness: 3/5 Patterson T, et al. Lancet. 2023 Oct 14;402(10410):1329-1337. Patients who sustain an out-of-hospital cardiac arrest without signs of ST elevation had no improvement in mortality or functional neurological outcomes when transported to...