Tenecteplase versus standard medical treatment for basilar artery occlusion within 24 h (TRACE-5): a multicentre, prospective, randomised, open-label, blinded-endpoint, superiority, phase 3 trial.

Tenecteplase versus standard medical treatment for basilar artery occlusion within 24 h (TRACE-5): a multicentre, prospective, randomised, open-label, blinded-endpoint, superiority, phase 3 trial.

Tenecteplase versus standard medical treatment for basilar artery occlusion within 24 h (TRACE-5): a multicentre, prospective, randomised, open-label, blinded-endpoint, superiority, phase 3 trial Xiong Y, Et al. Lancet. 2026 Feb 21;407(10530):763-772. doi:...
Comparison of inhalational methoxyflurane, intranasal fentanyl, and intravenous morphine for treatment of prehospital acute pain in Norway (PreMeFen): a randomised, non-inferiority, three-arm, phase 3 trial.

Comparison of inhalational methoxyflurane, intranasal fentanyl, and intravenous morphine for treatment of prehospital acute pain in Norway (PreMeFen): a randomised, non-inferiority, three-arm, phase 3 trial.

Comparison of inhalational methoxyflurane, intranasal fentanyl, and intravenous morphine for treatment of prehospital acute pain in Norway (PreMeFen): a randomised, non-inferiority, three-arm, phase 3 trial Simensen R, et al. Lancet. 2025 Dec 20;406(10522):2957-2967....
PTM Journal Club – Post-intubation Hypotension in Trauma Patients with Severe TBI

PTM Journal Club – Post-intubation Hypotension in Trauma Patients with Severe TBI

In this month’s Journal Club, we explored the impact of post-intubation hypotension for critically ill trauma patients with severe traumatic brain injury (TBI) in the prehospital setting.   Background and Study Objectives Trauma patients present with a variety of...