by Isaac Kim, Christian Vaillancourt | Jun 17, 2026 | Featured, Journal Club
Age-Adjusted D-Dimer Cutoff Levels to Rule Out Deep Vein Thrombosis. Le Gal G, et al. JAMA. 2026 Feb 3;335(5):416-424. doi: 10.1001/jama.2025.21561. Editorial: Like a Fine Wine—Aging the D-Dimer to Improve Value and Clinical Efficiency. Ujueta F, et...
by Sam Wilson, Venkatesh Thiruganasambandamoorthy | Jun 1, 2026 | Critical Care, Journal Club, Resuscitation
Personalized Hemodynamic Resuscitation Targeting Capillary Refill Time in Early Septic Shock: The ANDROMEDA-SHOCK-2 Randomized Clinical Trial. Hernandez G, ANDROMEDA-SHOCK-2 Investigators for the ANDROMEDA Research Network JAMA. 2025 Oct 29:e2520402. doi:...
by Stephen Hale, Venkatesh Thiruganasambandamoorthy | May 27, 2026 | Journal Club, Resuscitation
A Randomized Trial of Shared Decision-Making in Code Status Discussions Becker C, et al. NEJM Evid. 2025 May;4(5):EVIDoa2400422. doi: 10.1056/EVIDoa2400422. Methodology: 3.5/5 Usefulness: 3.5/5 Question and Methods: This multi-centre cluster-RCT...
by Meehan Andrew, Venkatesh Thiruganasambandamoorthy | May 25, 2026 | Journal Club, Neurology
Tenecteplase versus standard medical treatment for basilar artery occlusion within 24 h (TRACE-5): a multicentre, prospective, randomised, open-label, blinded-endpoint, superiority, phase 3 trial Xiong Y, Et al. Lancet. 2026 Feb 21;407(10530):763-772. doi:...
by Fiona Raymond, Ian Stiell | May 20, 2026 | ENT, Featured, Journal Club, Neurology
Diagnostic accuracy of the STANDING algorithm in patients with isolated vertigo: a multicentre prospective study (STANDING-M). Ronchetti M,et al. Emerg Med J. 2025 Nov 21;42(12):791-797. doi: 10.1136/emermed-2025-214902. Methodology: 4/5 Usefulness: 2.5/5 Question...
by Grace Northrop, Ian Stiell | May 18, 2026 | Anesthesiology, Featured, Journal Club, Pain Medicine
Comparison of inhalational methoxyflurane, intranasal fentanyl, and intravenous morphine for treatment of prehospital acute pain in Norway (PreMeFen): a randomised, non-inferiority, three-arm, phase 3 trial Simensen R, et al. Lancet. 2025 Dec 20;406(10522):2957-2967....
by Emily Cino, Ian Stiell | May 13, 2026 | Gastroenterology, Journal Club
Efficacy and Safety of Pharmacologic Therapies for Nausea and Emesis in the Emergency Department: A Systematic Review and Bayesian Network Meta-analysis. deSouza IS, et al. Ann Emerg Med. 2025 Dec;86(6):646-658. doi: 10.1016/j.annemergmed.2025.06.009. Methodology:...
by Gabrielle Ouellette, Christian Vaillancourt | May 11, 2026 | Anesthesiology, Journal Club, Ultrasound
Ultrasound-Guided Regional Anesthesia by Emergency Physicians for Hip Fractures and Delirium: A Randomized Clinical Trial Lee JS, et al. JAMA Netw Open. 2025 Dec 1;8(12):e2549337. doi: 10.1001/jamanetworkopen.2025.49337. Methodology: 4/5 Usefulness: 4/5 Question and...
by Madison Van Dusen, Christian Vaillancourt | May 7, 2026 | Critical Care, Journal Club, Resuscitation
Deferring Arterial Catheterization in Critically Ill Patients with Shock Muller G, et al. Deferring Arterial Catheterization in Critically Ill Patients with Shock. N Engl J Med. 2025 Nov 13;393(19):1875-1888 Editorial: A Less Invasive Approach to Intensive Care....
by Lucy Karp, Christian Vaillancourt | Apr 27, 2026 | Critical Care, Featured, Journal Club
A Crossover Trial of Hospital-Wide Lactated Ringer’s Solution versus Normal Saline McIntyre L, et al. Canadian Critical Care Trials Group. A Crossover Trial of Hospital-Wide Lactated Ringer’s Solution versus Normal Saline. N Engl J Med. 2025 Aug...
