Recently, Dr. Venkatesh Thiruganasambandamoorthy et al published the Canadian Syncope Risk Score, for the assessment of adult patients with syncope. He has previously helped provide some insight into the decision rule, and we now present an infographic and memory aid to help recall the score!Read More →
Journal Club Summary Seymour CW, et al. Journal N Engl J Med. 2017 Jun 8;376(23):2235-2244. EDITORIAL: State Sepsis Mandates – A New Era for Regulation of Hospital Quality. Hershey TB, et al. N Engl J Med. 2017 May 21. Methodology Score: 3.5/5 Usefulness Score: 3/5 This large retrospective review ofRead More →
Journal Club Summary Methodology Score: 4/5 Usefulness Score: 4.5/5 D’Onofrio G, et al JAMA. 2015 Apr 28;313(16):1636-44. Full Article This single, urban center RCT including 329 patients showed that buprenorphine initiated in the ED was more likely to increase engagement in addiction care at 30 days (78%) compared to referralRead More →
Journal Clubs Summary Methodology Score: 3/5 Usefulness Score: 3.5/5 Rehrer MW, et al. Ann Emerg Med. 2016 Nov;68(5):608-613. Abstract Link This single centre, randomized, triple-blinded, control trial did not demonstrate noninferiority of a single dose of dexamethasone compared to standard 5 day course of prednisone for adult asthma exacerbations. InRead More →
Journal Club Summary Methodology Score: 4/5 Usefulness Score: 4/5 Stanley AJ, et al. BMJ. 2017 Jan 4;356:i6432. Full Article Summary This multicentre, multinational study assessed the ability of five upper gastrointestinal bleeding scores to predict outcomes including death, re-bleeding, need for endoscopy, transfusion, surgery or interventional radiology, and length of hospital stay,Read More →
Journal Club Summary Methodology Score: 3/5 Usefulness Score: 3.5/5 Nijssen EC, et al Lancet. 2017 Feb 20. [Epub ahead of print] Abstract Link This prospective, open-label, single centre, randomized trial of 660 patients found no hydration (2.7% incidence CIN) to be non-inferior compared to iv hydration (2.6% incidence CIN) in preventing contrast inducedRead More →
Journal Club Summary Methodology Score: 4/5 Usefulness Score: 3/5 Lascarrou JB, et al. JAMA. 2017 Feb 7;317(5):483-493. Abstract Link This study was an open-label, randomized clinical trial conducted at 7 ICUs in France that found video laryngoscopy compared with direct laryngoscopy did not improve first-pass orotracheal intubation rates or medianRead More →
Journal Club Summary Methodology Score: 4/5 Usefulness Score: 3.5/5 Hinson JS, et al. Ann Emerg Med. 2017 Jan 19 [Epub ahead of print] Full Article In this large, well-designed retrospective study of AKI following contrast administration for CT in ED patients, IV contrast was not found to be associated withRead More →
Summary Methodology Score: 4/5 Usefulness Score: 3.5/5 Patel BK, et al. JAMA. 2016 Jun 14;315(22):2435-41 Full Article Editorial: Unmasking a Role for Noninvasive Ventilation in Early Acute Respiratory Distress Syndrome. Beitler JR, et al. JAMA. 2016 Jun 14;315(22):2401-3. This single-centre, non-blinded RCT of ICU ARDS patients, found that noninvasive ventilation (NIV)Read More →
Journal Club Summary Methodology Score: 4/5 Usefulness Score: 2/5 Miller LG, et al. N Engl J Med. 2015 Mar 19;372(12):1093-103. Full Article Editorial: Choosing an antibiotic for skin infections. Wessels MR N Engl J Med. 2015 Mar 19;372(12):1164-5. http://www.nejm.org/doi/full/10.1056/NEJMe1500331 This multicenter, prospective, randomized, double-blind trial compared the treatment of uncomplicated skin infections with clindamycinRead More →