by emottawa | Dec 8, 2014 | Journal Club
Journal Club Summary Landmark Series Methodology Score: 4/5 Usefulness Score: 4.5/5 Righini M, et al. JAMA. 2014 Mar 19;311(11):1117-24 Full Article This prospective multicenter European prospective cohort study found that using age-adjusted...
by emottawa | Dec 1, 2014 | Journal Club
Journal Club Summary Landmark Series Methodology Score: 4/5 Usefulness Score: 4.5/5 Kline JA, et al. J Thromb Haemost. 2008 May;6(5):772-80. Full Article In this prospective multicenter validation study, the PERC rule was found to have a sensitivity of 97.4% (CI...
by emottawa | Nov 17, 2014 | Journal Club
Journal Club Summary Methodology Score: 3/5 Usefulness Score: 3.5/5 Jabre P, et al. N Engl J Med. 2013 Mar 14;368(11):1008-18 Article Link This out of hospital, French randomized controlled trial found that when family members were given the option of viewing ongoing...
by emottawa | Nov 12, 2014 | Journal Club
Journal Club Summary Methodology Score: 3.5/5 Usefulness Score: 2.5/5 Scheuermeyer FX, Innes G, Grafstein E, Kiess M, Boychuk B, Yu E, Kalla D, Christenson J. Ann Emerg Med. 2012 Apr;59(4):256-264.e3. Abstract Link This prospective single-centre...
by emottawa | Nov 3, 2014 | Journal Club
Journal Club Summary Landmark Series Methodology Score: 3.5/5 Usefulness Score: 3.5/5 Sprung CL, et al. CORTICUS Study Group. N Engl J Med. 2008 Jan 10;358(2):111-24 Article Link This Multicenter, double-blind, parallel-group, placebo-controlled RCT...
by emottawa | Oct 27, 2014 | Journal Club
Journal Club Summary Landmark Series Methodology Score: 4/5 Usefulness Score: 4/5 ProCESS Investigators N Engl J Med. 2014 May 1;370(18):1683-93. Abstract Link This large multicentre U.S. RCT of 1341 septic patients found no significant differences in mortality...
by emottawa | Oct 20, 2014 | Journal Club
Journal Club Summary Methodology Score: 3/5 Usefulness Score: 2.5/5 Chamberlain JM, et al; Pediatric Emergency Care Applied Research Network (PECARN). JAMA.2014 Apr 23-30;311(16):1652-60. doi: 10.1001/jama.2014.2625. Full Article This double-blind, multi-center,...
by emottawa | Sep 30, 2014 | Journal Club
Journal Club Summary Methodology Score: 4/5 Usefulness Score: 4/5 Leuppi JD, et al. JAMA. 2013 Jun 5;309(21):2223-31. Article Link This multicenter, double blinded trial demonstrated non-inferiority of a 5-day course of 40mg prednisone versus a...
by emottawa | Sep 22, 2014 | Journal Club
Journal Club Summary Methodology Score: 3.5/5 Usefulness Score: 2.5/5 Caironi P, Tognoni G, et al. the ALBIOS Study Investigators. N Engl J Med. 2014 Mar 18. Abstract Link This was an open-label RCT of 1,800 ICU patients with severe sepsis or septic...
by emottawa | Sep 15, 2014 | Journal Club
Journal Club Summary Methodology Score: 4/5 Usefulness Score: 2/5 Verhaegen J, Gallos ID, van Mello NM, Abdel-Aziz M, Takwoingi Y, Harb H, Deeks JJ, Mol BW, Coomarasamy A BMJ. 2012 Sep 27;345:e6077 Article Link This thorough and well performed...
