epi lesson Archives

Targeted temperature management at 33°C versus 36°C after cardiac arrest

by emottawa | Mar 31, 2014 | Journal Club

Journal Club Summary Landmark Article Series Nielsen N, et al.; TTM Trial Investigators. N Engl J Med. 2013 Dec 5;369(23):2197-206. Methodology Score: 5/5 Usefulness Score: 5/5 Article Link In this multicenter, international RCT of...

Clopridogrel with Aspirin in Acute Minor Stroke or Transient Ischemic Attack

by emottawa | Mar 24, 2014 | Journal Club

Journal Club Summary Methodology Score: 4 /5 Usefulness Score: 3.5/5 Wang Y, Johnston SC, Wang Y. N Engl J Med. 2013 Oct 3;369(14):1376-7. Article Link This multicenter randomized-control trial of 5,100 patients with TIA/minor stroke treated...

Efficacy and safety of the novel oral anticoagulants in atrial fibrillation: a systematic review and meta-analysis of the literature

by emottawa | Mar 17, 2014 | Journal Club

Journal Club Summary Methodology Score: 4.5/5 Usefulness Score: 3/5 Dentali F, Riva N, Crowther M, Turpie AG, Lip GY, Ageno W. Circulation. 2012 Nov 13;126(20):2381-91. Article Link This was a systematic review and meta-analysis of 12 phase II/III...

A new and rapid method for epistaxis treatment using injectable form of tranexamic acid topically: a randomized controlled trial

by emottawa | Mar 10, 2014 | Journal Club

Journal Club Summary Methodology Score: 2/5 Usefulness Score: 3.5/5 Zahed R, Moharamzadeh P, Alizadeharasi S, Ghasemi A, Saeedi M.Am J Emerg Med.2013 Sep;31(9):1389-92 Abstract Link This single centre, ED based, parallel group randomized control trial...

The benefits of steroids versus steroids plus antivirals for treatment of Bell’s palsy: a meta-analysis

by emottawa | Mar 3, 2014 | Journal Club

Journal Club Summary Methodology Score: 3.5/5 Usefulness Score: 3.5/5 Quant EC, Jeste SS, Muni RH, Cape AV, Bhussar MK, Peleg AY. BMJ. 2009 Sep 7;339:b3354. doi: 10.1136/bmj.b3354. Article Link This meta-analysis of randomized controlled trials comparing...