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Fibrinolysis for patients with intermediate-risk pulmonary embolism

by emottawa | Dec 15, 2014 | Journal Club

Journal Club Summary Methodology Score: 3.5/5               Usefulness Score: 3/5   PEITHO Investigators. N Engl J Med. 2014 Apr 10;370(15):1402-11. Article Link   This multicentre double blind RCT focused on patients with submassive pulmonary embolism and the use of...

Age-adjusted D-dimer cutoff levels to rule out pulmonary embolism: the ADJUST-PE study

by emottawa | Dec 8, 2014 | Journal Club

Journal Club Summary Landmark Series Methodology Score: 4/5                  Usefulness Score: 4.5/5   Righini M, et al. JAMA. 2014 Mar 19;311(11):1117-24  Full Article   This prospective multicenter European prospective cohort study found that using age-adjusted...

Outpatient versus inpatient treatment for patients with acute pulmonary embolism: an international, open-label, randomised, non-inferiority trial

by emottawa | Sep 8, 2014 | Journal Club

Journal Club Summary Methodology Score: 4/5  Usefulness Score:  3.5/5 Aujesky D, et al. Lancet. 2011 Jul 2;378(9785):41-8. Abstract Link   This open label, randomized, un-blinded, multi-centered trial compared inpatient vs. outpatient treatment of low-risk PE showed...

Safe exclusion of pulmonary embolism using the Wells rule and qualitative D-dimer testing in primary care: prospective cohort study.

by emottawa | Apr 7, 2014 | Journal Club

Journal Club Summary Methodology Score: 3/5                  Usefulness Score: 2.5/5   Geersing GJ, et al. BMJ. 2012 Oct 4;345:e6564. Article Link   This was a prospective cohort validation study using the Wells clinical decision rule combined with D-dimer to exclude...

Prognostic value of plasma lactate levels among patients with acute pulmonary embolism: the thrombo-embolism lactate outcome study

by emottawa | Apr 8, 2013 | Journal Club, Uncategorized

Journal Club Summary Prognostic value of plasma lactate levels among patients with acute pulmonary embolism: the thrombo-embolism lactate outcome study Methodology: 3/5           Usefulness: 2/5 Vanni S, Viviani G, Baioni M, Pepe G, Nazerian P, Socci F, Bartolucci M,...
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