Ultrasound-Guided Regional Anesthesia by Emergency Physicians for Hip Fractures and Delirium: A Randomized Clinical Trial

Lee JS, et al. JAMA Netw Open. 2025 Dec 1;8(12):e2549337. doi: 10.1001/jamanetworkopen.2025.49337.

Methodology: 4/5
Usefulness: 4/5

Question and Methods: Does training emergency physicians to perform ultrasound-guided regional anesthesia for hip fractures reduces incident delirium using a multicenter stepped-wedge cluster randomized trial. 

Findings: UGRA use increased from ~2% to ~53% after training and was associated with reduced incident delirium (adjusted OR ≈0.72, 95% CI), without affecting delirium duration and with minimal complications. 
Limitations: Open-label design, lower than anticipated sample size, incomplete block delivery, and large site variation in in incidence of delirium. 
Interpretation: 
This study supports ED-performed UGRA as a feasible, low-risk intervention that can meaningfully reduce delirium risk in older hip fracture patients and should be considered for routine ED practice. 

For more on performing a hip block, read on the SIFI block here, and IIFI block here.

 

 

 

Authors

  • Gabrielle Ouellette

    Dr. Gabrielle Ouellette is a CCFP-EM Resident at the time of this post, at the University of Ottawa.

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  • Christian Vaillancourt

    Senior Scientist, Clinical Epidemiology Program
    Ottawa Hospital Research Institute
    Full Professor, Emergency Medicine
    University of Ottawa
    Research Chair in Emergency Cardiac Resuscitation, Emergency Medicine
    University of Ottawa
    Associate Medical Director, Regional Paramedic Program for Eastern Ontario

    Research Interests:
    Dr. Vaillancourt's current research program focuses on pre-hospital care, specifically improving care and survival for cardiac arrest and trauma victims.

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