by Michael Hale, Pascale King | Feb 27, 2020 | Featured
Community-acquired pneumonia is the leading infectious cause of death in Canada, and combined with influenza is the 7th most common cause of death overall. Diagnosis The 3 main pillars leading to the diagnosis of pneumonia are as follow: Evidence of infection (fever,...
by Hans Rosenberg | Feb 17, 2020 | Infectious Disease, Journal Club, Respirology
Methodology: 4/5 Usefulness: 2/5 Alexander E., et al. JAMA. 2019 Sep 27. doi: 10.1001/jama.2019.15468. Editorial: Lefamulin-A New Antibiotic for Community-Acquired Pneumonia. Question and Methods: LEAP-2 was a phase 3, double-blinded RCT to determine non-inferiority...
by emottawa | Aug 15, 2016 | Journal Club
Journal Club Summary Methodology Score: 4/5 Usefulness Score: 3.5/5 Siemieniuk RA, et al. Ann Intern Med. 2015;163(7):519-528. Abstract Link This is a well-done systematic review & meta-analysis elucidating whether corticosteroid therapy...
by emottawa | Aug 31, 2015 | Journal Club
Journal Club Summary Methodology Score: 3/5 Usefulness Score: 2/5 Blum CA, Nigro N Briel M, et al. Lancet. 2015 Jan 16. pii: S0140-6736(14)62447-8. Abstract Link This randomized, double-blinded, placebo-controlled trial demonstrated an improved time to ‘clinical...
