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A Randomized Trial of Icatibant in ACE-Inhibitor–Induced Angioedema

by emottawa | Sep 28, 2015 | Journal Club

Journal Club Summary Methodology Score: 1.5/5                 Usefulness Score: 1/5   Baş M, Greve J, Stelter K, et al. N Engl J Med. 2015 Jan 29;372(5):418-25 Full Article   This small phase 2, multicenter, double blind randomized trial of 30 ED patients found a...

Association of Pyuria and Clinical Characteristics With the Presence of Urinary Tract Infection Among Patients With Acute Nephrolithiasis

by emottawa | Sep 21, 2015 | Journal Club

Journal Club Summary Methodology Score:    2.5/5                 Usefulness Score:  2.5/5  Abrahamian FM, Krishnadasan A, Mower WR, et al. Ann Emerg Med. 2013 Nov;62(5):526-33. Abstract Link   Pyuria alone cannot be used to determine if UTI is present in patients with...

Intensive blood pressure reduction in acute intracerebral haemorrhage: a meta-analysis

by emottawa | Sep 7, 2015 | Journal Club

Journal Club Summary Methodology Score: 3/5                    Usefulness Score:  3/5   Tsivgoulis G, Katsanos AH, Butcher KS, et al. Neurology. 2014 Oct 21;83(17):1523-9 Abstract Link    This systematic review and meta-analysis of 4 RCTs found that mortality rates...

Adjunct prednisone therapy for patients with community-acquired pneumonia: a multicentre, double-blind, randomised, placebo-controlled trial.

by emottawa | Aug 31, 2015 | Journal Club

Journal Club Summary Methodology Score: 3/5 Usefulness Score: 2/5 Blum CA, Nigro N Briel M, et al. Lancet. 2015 Jan 16. pii: S0140-6736(14)62447-8. Abstract Link This randomized, double-blinded, placebo-controlled trial demonstrated an improved time to ‘clinical...

Clinical prediction model to aid emergency doctors managing febrile children at risk of serious bacterial infections: diagnostic study

by emottawa | Aug 17, 2015 | Journal Club

Journal Club Summary Methodology Score: 2.5/5 Usefulness Score: 2/5 Nijman RG, et al. BMJ. 2013 Apr 2;346:f1706.  Full Article This was a derivation, cross-validation, and external validation of a decision rule for the febrile pediatric patient to identify who is at...
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