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Vasopressin, Steroids, and Epinephrine and Neurologically Favorable Survival After In-Hospital Cardiac Arrest A Randomized Clinical Trial

by emottawa | Jan 13, 2014 | Journal Club

Journal Club Summary Methodology Score: 4/5                 Usefulness Score: 2.5/5   Mentzelopoulos SD, et al. JAMA. 2013;310(3):270-279. Article Link   This randomized, multi-centered, double blind, placebo controlled trial compared vasopressin, steroids and...

Comparison of dopamine and norepinephrine in the treatment of shock.

by EMOttawa | Jan 6, 2014 | Journal Club, landmark

Journal Club Summary Landmark Series Methodology Score: 4/5                 Usefulness Score: 4/5 De Backer D, Biston P, Devriendt J, Madl C, Chochrad D, Aldecoa C, Brasseur A, Defrance P, Gottignies P, Vincent JL; SOAP II Investigators. N Engl J Med. 2010 Mar...

Short-term vs Conventional Glucocorticoid Therapy in Acute Exacerbations of Chronic Obstructive Pulmonary Disease: the REDUCE randomized clinical trial

by emottawa | Dec 23, 2013 | Journal Club

Journal Club Summary Methodology Score: 4/5                 Usefulness Score: 3.5/5   Leuppi JD, Schuetz P, Bingisser R, Bodmer M, Briel M, Drescher T, et al. JAMA. 2013 Jun 5;309(21):2223-31 Article Link   This multicentre, Swiss-based RCT adds to the literature that...

How Do I Perform a Lumbar Puncture and Analyze the Results to Diagnose Bacterial Meningitis?

by emottawa | Dec 16, 2013 | Journal Club

Journal Club Summary Landmark Article Series – UPDATE   Methodology Score: 2.5/5              Usefulness Score: 4/5 Straus SE, Thorpe KE, Holroyd-Leduc J. JAMA. 2006 Oct 25;296(16):2012-22.   Article Link   This overview article from the JAMA Rational Clinical...

A 2-h diagnostic protocol to assess patients with chest pain symptoms in the Asia-Pacific region (ASPECT): a prospective observational validation study

by emottawa | Dec 9, 2013 | Journal Club

Journal Club Summary Methodology Score: 4/5                 Usefulness Score: 3/5   Than M, Cullen L, Reid CM, Lim SH, Aldous S, Ardagh MW, et al. Lancet. 2011 Mar 26;377(9771):1077-84.  Abstract Link    This prospective multicentre cohort study attempted to validate...
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