PE Archives

An Age-Adjusted D-dimer Threshold for Emergency Department Patients With Suspected Pulmonary Embolus: Accuracy and Clinical Implications.

by emottawa | Dec 21, 2015 | Journal Club

Journal Club Summary Methodology Score: 3/5 Usefulness Score: 3/5 Sharp AL, Vinson DR, Alamshaw F, Handler J, Gould MK. Ann Emerg Med. 2015 Aug 27. pii: S0196-0644(15)00616-2. Abstract Link Retrospective study of 31,094 patients investigated for PE,...

Thrombolysis for Pulmonary Embolism and Risk of All-Cause Mortality, Major Bleeding, and Intracranial Hemorrhage: A meta-analysis

by emottawa | Jan 5, 2015 | Journal Club

Journal Club Summary Methodology Score: 4.5/5 Usefulness Score: 3/5 Chatterjee S, Chakraborty A, Weinberg I, Kadakia M, Wilensky RL, Sardar P, Kumbhani DJ, Mukherjee D, Jaff MR, Giri J. JAMA. 2014 Jun 18;311(23):2414-21. Article Link This...

Fibrinolysis for patients with intermediate-risk pulmonary embolism

by emottawa | Dec 15, 2014 | Journal Club

Journal Club Summary Methodology Score: 3.5/5 Usefulness Score: 3/5 PEITHO Investigators. N Engl J Med. 2014 Apr 10;370(15):1402-11. Article Link This multicentre double blind RCT focused on patients with submassive pulmonary embolism and the use of...

Age-adjusted D-dimer cutoff levels to rule out pulmonary embolism: the ADJUST-PE study

by emottawa | Dec 8, 2014 | Journal Club

Journal Club Summary Landmark Series Methodology Score: 4/5 Usefulness Score: 4.5/5 Righini M, et al. JAMA. 2014 Mar 19;311(11):1117-24 Full Article This prospective multicenter European prospective cohort study found that using age-adjusted...

Outpatient versus inpatient treatment for patients with acute pulmonary embolism: an international, open-label, randomised, non-inferiority trial

by emottawa | Sep 8, 2014 | Journal Club

Journal Club Summary Methodology Score: 4/5 Usefulness Score: 3.5/5 Aujesky D, et al. Lancet. 2011 Jul 2;378(9785):41-8. Abstract Link This open label, randomized, un-blinded, multi-centered trial compared inpatient vs. outpatient treatment of low-risk PE showed...