by emottawa | Nov 3, 2014 | Journal Club
Journal Club Summary Landmark Series Methodology Score: 3.5/5 Usefulness Score: 3.5/5 Sprung CL, et al. CORTICUS Study Group. N Engl J Med. 2008 Jan 10;358(2):111-24 Article Link This Multicenter, double-blind, parallel-group, placebo-controlled RCT...
by emottawa | Sep 22, 2014 | Journal Club
Journal Club Summary Methodology Score: 3.5/5 Usefulness Score: 2.5/5 Caironi P, Tognoni G, et al. the ALBIOS Study Investigators. N Engl J Med. 2014 Mar 18. Abstract Link This was an open-label RCT of 1,800 ICU patients with severe sepsis or septic...
by emottawa | Sep 1, 2014 | Journal Club
Journal Club Summary Methodology Score: 2.5/5 Usefulness Score: 2/5 Schortgen F, et al. Am J Respir Crit Care Med. 2012 May 15;185(10):1088-95 Full Article This randomized, non-blinded trial found in an ICU population that external cooling in...
by emottawa | Apr 14, 2014 | Journal Club
Journal Club Summary Methodology Score: 4/5 Usefulness Score: 2/5 Morelli A, et al. JAMA. 2013 Oct 23;310(16):1683-91 Article Link This single centre phase 2B trial randomized septic patients still requiring vasopressors after 24hrs of EGDT to...
by EMOttawa | Oct 23, 2012 | Journal Club, landmark
Journal Club Summary Methodology Score: 3.5/5 Usefulness Score: 4/5 De Backer D, Aldecoa C, Njimi H, Vincent JL. Crit Care Med. 2012 Mar;40(3):725-30. Article Link This meta-analysis of 6 trials found that in patients with septic shock, dopamine administration was...
