Safety and Efficacy of Hydromorphone as an Analgesic Alternative to Morphine in Acute Pain: A Randomized Clinical Trial
Journal Club Summary
Andrew K Chang, Polly E Bijur, Robert H Meyer, Mark K Kenny, Clemencia Solorzano, and E John Gallagher
This U.S. randomized trial in ED adults with severe pain found similar effectiveness for intravenous hydromorphone [0.015 mg/kg] and iv morphine [0.1 mg/kg]. This was a well-done study and many JC attendees professed their enthusiasm for hydromorphone as an alternative to morphine for severe pain.