Journal Club Summaryfactor VII

Landmark Series
Mayer SA, Brun NC, Begtrup K, Broderick J, Davis S, Diringer MN, et al. N Engl J Med. 2008 May 15;358(20):21 

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This industry sponsored, international multicentre RCT involved 841 patients with acute ICH and found that Factor VII was associated with a reduced growth in hematoma size but no improvement in survival or function and an increase in arterial serious adverse events. There appears to be no role for Factor VII in acute ICH.