Journal Club Summary
Methodology Score: 4/5
Usefulness Score: 3.5/5
Castellucci LA, et al. JAMA. 2014 Sep 17;312(11):1122-35.
Epi Lesson: Network Meta-analysis
Network meta-analyses should not be viewed as the same as other meta-analyses. This specialized methodology is designed to answer complex management questions when there are multiple options possible. This is particularly helpful when a head-to-head RCT is not practical to conduct. The key requirement is that the studies being compared have at least one common or equivalent therapy among them.