Methodology: 3/5          
Usefulness: 2.5/5

Gaydos CA et al. Ann Emerg Med. 2019 Jul;74(1):36-44. doi: 10.1016/j.annemergmed.2018.09.012. Epub 2018 Nov 2.

Question and Methods: RCT of women receiving pelvic testing for CT/NG comparing standard of care test (NAAT) vs. POC test (GeneXpert). Treatment was at the discretion of the clinician

Findings:

  • CT undertreatment rate difference –46.2%; 95% CI -73.3% to -19.2%
  • NG undertreatment rate difference –57.1%; 95% CI -93.8% to -20.5%
  • CT Overtreatment rate difference –23.4%; 95% CI –35.3% to –11.5%
  • NG Overtreatment rate difference –21.3%; 95% CI –33.1% to –9.5%

Limitations: Single urban inner city ED with small sample sizes; patients in rapid test group not required to wait for results; patients treated at clinician discretion.

Interpretation: Point of care testing for STI may optimize treatment and be of particular benefit in certain populations but more research is needed.

By: Dr. Lindsay Cheskes

Hans Rosenberg
Dr. Rosenberg is an emergency physician at the Ottawa Hospital, assistant professor at the University of Ottawa, and Director of the Digital Scholarship and Knowledge Dissemination Program.