Methodology: 4.5/5
Usefulness: 4.5/5

Thiruganasambandamoorthy V, et al. JAMA Intern Med. 2020 Mar 23;180(5):1-8. 

Question and Methods: Prospective cohort validation to predict 30-day serious outcomes among ED patients with syncope

Findings: 3819 patients had an overall 3.6% serious event rate at 30-days. At a score of -1, the CSRS had a Sn/Sp/NPV of 97.8%/44.3%/100%

Limitations:
Overlap in recruitment sites and Canadian sites only may limit generalizability. There are few patients in the high-risk categories

Interpretation:
The validation of the CSRS is key to the risk stratification and disposition of syncope patients. Very low & low risk patients can be discharged with exceptionally low rate of serious outcomes

By: Dr. Shawn Chhabra

Hans Rosenberg
Dr. Rosenberg is an emergency physician at the Ottawa Hospital, assistant professor at the University of Ottawa, and Director of the Digital Scholarship and Knowledge Dissemination Program.