Methodology: 2/5          
Usefulness: 2/5 

Shipman S, et al. Ann Emerg Med. 2021 Mar;77(3):338-344. doi: 10.1016/j.annemergmed.2020.08.036. 

Question and Methods: Double blinded RCT comparing tetracaine versus placebo eye drops for 24 hours in the treatment of pain for uncomplicated corneal abrasions.
Findings: Significant 6.1 point reduction in pain score and no increase in complication rate in the tetracaine group compared to placebo.
Limitations: Single-center study with poor 1 week follow-up and not actually powered to establish safety of tetracaine eye drops.

Interpretation: Tetracaine eye drops for 24 hours are effective and may be safe in the reliable patient with uncomplicated corneal abrasion and timely ophthalmology follow-up.

By: Dr. Yang Guo

Hans Rosenberg
Dr. Rosenberg is an emergency physician at the Ottawa Hospital, assistant professor at the University of Ottawa, and Director of the Digital Scholarship and Knowledge Dissemination Program.