by emottawa | Aug 11, 2014 | Journal Club
Journal Club Summary Methodology Score: 2.5/5 Usefulness Score: 2.5/5 Downie A, et al. BMJ 2013;347:f7095 Article Link This Cochrane review of the diagnostic accuracy of red flags for fracture or malignancy in patients with low back pain in multiple...
by emottawa | Aug 4, 2014 | Journal Club
Journal Club Summary Landmark Series Methodology Score: 4/5 Usefulness Score: 4/5 CRASH-2 trial collaborators Lancet. 2010 Jul 3;376(9734):23-32. Article Link This large RCT assessed the effect of early administration of tranexamic acid to trauma...
by emottawa | Jul 28, 2014 | Journal Club
Journal Club Summary Methodology Score: 4/5 Usefulness Score: 2/5 Bateman DN, et al. Lancet. 2014 Feb 22;383(9918):697-704 Article Link This 2×2 factorial, intention to treat, randomized controlled trial of paracetamol overdose showed a...
by emottawa | Jul 21, 2014 | Journal Club
Journal Club Summary Methodology Score: 4/5 Usefulness Score: 2/5 INTERACT2 Investigators. N Engl J Med. 2013 Jun 20;368(25):2355-65. Article Link This large multicentre, partially blinded RCT compared aggressively lowering SBP to <140 vs....
by emottawa | Jul 14, 2014 | Journal Club
Journal Club Summary Methodology Score: 4.5/5 Usefulness Score: 3.5/5 Harman S, Zemek R, Duncan MJ, Ying Y, Petrcich W. CMAJ. 2013 Sep 17;185(13):E629-34. Article Link This study was a double blind RCT which demonstrated that using topical LET on...
by emottawa | Apr 21, 2014 | Journal Club
Journal Club Summary Methodology Score: 4/5 Usefulness Score: 4/5 Blyth L, Atkinson P, Gadd K, Lang E. Acad Emerg Med. 2012 Oct;19(10):1119-26. Article Link This systematic review of 8 studies found that when transthoracic ultrasound is performed...
by emottawa | Apr 14, 2014 | Journal Club
Journal Club Summary Methodology Score: 4/5 Usefulness Score: 2/5 Morelli A, et al. JAMA. 2013 Oct 23;310(16):1683-91 Article Link This single centre phase 2B trial randomized septic patients still requiring vasopressors after 24hrs of EGDT to...
by emottawa | Apr 7, 2014 | Journal Club
Journal Club Summary Methodology Score: 3/5 Usefulness Score: 2.5/5 Geersing GJ, et al. BMJ. 2012 Oct 4;345:e6564. Article Link This was a prospective cohort validation study using the Wells clinical decision rule combined with D-dimer to exclude...
by emottawa | Mar 31, 2014 | Journal Club
Journal Club Summary Landmark Article Series Nielsen N, et al.; TTM Trial Investigators. N Engl J Med. 2013 Dec 5;369(23):2197-206. Methodology Score: 5/5 Usefulness Score: 5/5 Article Link In this multicenter, international RCT of...
by emottawa | Mar 24, 2014 | Journal Club
Journal Club Summary Methodology Score: 4 /5 Usefulness Score: 3.5/5 Wang Y, Johnston SC, Wang Y. N Engl J Med. 2013 Oct 3;369(14):1376-7. Article Link This multicenter randomized-control trial of 5,100 patients with TIA/minor stroke treated...
