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Comparison of dopamine and norepinephrine in the treatment of shock.

by EMOttawa | Jan 6, 2014 | Journal Club, landmark

Journal Club Summary Landmark Series Methodology Score: 4/5                 Usefulness Score: 4/5 De Backer D, Biston P, Devriendt J, Madl C, Chochrad D, Aldecoa C, Brasseur A, Defrance P, Gottignies P, Vincent JL; SOAP II Investigators. N Engl J Med. 2010 Mar...

Short-term vs Conventional Glucocorticoid Therapy in Acute Exacerbations of Chronic Obstructive Pulmonary Disease: the REDUCE randomized clinical trial

by emottawa | Dec 23, 2013 | Journal Club

Journal Club Summary Methodology Score: 4/5                 Usefulness Score: 3.5/5   Leuppi JD, Schuetz P, Bingisser R, Bodmer M, Briel M, Drescher T, et al. JAMA. 2013 Jun 5;309(21):2223-31 Article Link   This multicentre, Swiss-based RCT adds to the literature that...

How Do I Perform a Lumbar Puncture and Analyze the Results to Diagnose Bacterial Meningitis?

by emottawa | Dec 16, 2013 | Journal Club

Journal Club Summary Landmark Article Series – UPDATE   Methodology Score: 2.5/5              Usefulness Score: 4/5 Straus SE, Thorpe KE, Holroyd-Leduc J. JAMA. 2006 Oct 25;296(16):2012-22.   Article Link   This overview article from the JAMA Rational Clinical...

A 2-h diagnostic protocol to assess patients with chest pain symptoms in the Asia-Pacific region (ASPECT): a prospective observational validation study

by emottawa | Dec 9, 2013 | Journal Club

Journal Club Summary Methodology Score: 4/5                 Usefulness Score: 3/5   Than M, Cullen L, Reid CM, Lim SH, Aldous S, Ardagh MW, et al. Lancet. 2011 Mar 26;377(9771):1077-84.  Abstract Link    This prospective multicentre cohort study attempted to validate...

Intravenous Droperidol or Olanzapine as an Adjunct to Midazolam for the Acutely Agitated Patient: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Trial

by emottawa | Dec 2, 2013 | Journal Club

Journal Club Summary Methodology Score: 3/5                 Usefulness Score: 2/5   Chan EW, Taylor DM, Knott JC, Phillips GA, Castle DJ, Kong DC. Ann Emerg Med. 2013 Jan;61(1):72-81   Abstract Link   This randomized, double-blind, double dummy study comparing...

Validation of the Simplified Motor Score in the Out-of-Hospital Setting for the Prediction of Outcomes After Traumatic Brain Injury

by emottawa | Nov 25, 2013 | Journal Club

Journal Club Summary Methodology score: 3/5 Usefulness score: 2/5 Thompson DO, Hurtado TR, Liao MM, Byyny RL, Gravitz C, Haukoos JS. Ann Emerg Med. 2011 Nov;58(5):417-25 Article Link   This retrospective registry study demonstrated poor performance of either the...

Hydroxyethyl Starch 130/0.42 versus Ringer’s Acetate in Severe Sepsis

by EMOttawa | Nov 18, 2013 | Journal Club, landmark

Journal Club Summary Landmark Series Methodology Score: 4/5                 Usefulness Score: 4.5/5   Perner A, et al.; 6S Trial Group; Scandinavian Critical Care Trials Group. N Engl J Med. 2012 Jul 12;367(2):124-34   Article Link   This multi-centre, double-blind,...

Meta-analysis of Usefulness of D-dimer to Diagnose Acute Aortic Dissection

by emottawa | Nov 11, 2013 | Journal Club

Journal Club Summary Methodology Score: 3/5                 Usefulness Score: 3/5   Shimony A, Filion KB, Mottillo S, Dourian T, Eisenberg MJ. Am J Cardiol. 2011 Apr 15;107(8):1227-34   Abstract Link   This meta-analysis of seven studies shows a pooled sensitivity...

Lactate Clearance vs Central Venous Oxygen Saturation as Goals of Early Sepsis Therapy: a Randomized Clinical Trial

by emottawa | Nov 4, 2013 | Journal Club

Journal Club Summary Methodology Score: 3.5/5               Usefulness Score: 3.5/5   Jones AE, Shapiro NI, Trzeciak S, Arnold RC, Claremont HA, Kline JA; Emergency Medicine Shock Research Network (EMShockNet) Investigators. JAMA. 2010 Feb 24;303(8):739-46.  Article...

Transfusion Strategies for Acute Upper Gastrointestinal Bleeding

by EMOttawa | Oct 28, 2013 | Journal Club, landmark

Journal Club Summary Landmark Series Methodology Score: 3.5/5               Usefulness Score: 4/5   Villanueva C, Colomo A, Bosch A, Concepción M, Hernandez-Gea V, Aracil C, Graupera I, Poca M, Alvarez-Urturi C, Gordillo J, Guarner-Argente C, Santaló M, Muñiz E,...
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