Journal Club Archives

Ketamine-propofol combination (ketofol) versus propofol alone for emergency department procedural sedation and analgesia: a randomized double-blind trial

by emottawa | Feb 12, 2013 | Journal Club

Journal Club Summary Methodology: 4/5 Usefulness: 3/5 Andolfatto G, Abu-Laban RB, Zed PJ, Staniforth SM, Stackhouse S, Moadebi S, Willman E. Ann Emerg Med. 2012 Jun;59(6):504-12.e1-2. Abstract Link This double-blind, randomized trial found that Ketofol does not...

The risk of catheter-related bloodstream infection with femoral venous catheters as compared to subclavian and internal jugular venous catheters: a systematic review of the literature and meta-analysis

by emottawa | Feb 4, 2013 | Journal Club

Journal Club Summary Methodology: 1/5 Usefulness: 3/5 Marik PE, Flemmer M, Harrison W. Crit Care Med. 2012 Aug;40(8):2479-85 Pub Med Link This systematic review and meta-analysis concluded that there is no significant difference in the rates of...

The benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke trial [IST-3]): a randomised controlled trial

by emottawa | Jan 29, 2013 | Journal Club

Journal Club Summary Methodology: 2.5/5 Usefulness: 2.5/5 IST-3 collaborative group, Sandercock P, Wardlaw JM, et al. Lancet. 2012 Jun 23;379(9834):2352-63. Article Link This international, multicenter, randomized, open-treatment trial was aimed at detecting...

CT angiography for safe discharge of patients with possible acute coronary syndromes

by emottawa | Jan 21, 2013 | Journal Club

Journal Club Summary Methodology: 4/5 Usefulness: 2/5 Litt HI, Gatsonis C, Snyder B, Singh H, Miller CD, Entrikin DW, Leaming JM, Gavin LJ, Pacella CB, Hollander JE. New England Journal of Medicine, 2012 Apr 12;366(15):1393-403. Article Link This...

A randomized trial of tenecteplase versus alteplase for acute ischemic stroke

by emottawa | Jan 14, 2013 | Journal Club

Journal Club Summary Methodology: 3/5 Usefulness: 3/5 Parsons M, Spratt N, Bivard A, Campbell B, Chung K, Miteff F, O’Brien B, Bladin C, McElduff P, Allen C, Bateman G, Donnan G, Davis S, Levi C. N Engl J Med. 2012 Mar 22;366(12):1099-107....

Clinical decision rules for adults with minor head injury: a systematic review

by emottawa | Jan 9, 2013 | Journal Club

Journal Club Summary Methodology: 3.5/5 Usefulness: 4/5 Harnan SE, Pickering A, Pandor A, Goodacre SW. J Trauma. 2011 Jul;71(1):245-51 PubMed Link This systematic review compared the diagnostic accuracies of clinical decision rules for adults...

Hydroxyethyl starch or saline for fluid resuscitation in intensive care

by EMOttawa | Dec 19, 2012 | Journal Club, landmark

Journal Club Summary Methodology: 4/5 Usefulness: 3.5/5 Myburgh JA, Finfer S, Bellomo R, Billot L, Cass A, Gattas D, Glass P, Lipman J, Liu B, McArthur C, McGuinness S, Rajbhandari D, Taylor CB, Webb SA; CHEST Investigators; Australian and New Zealand Intensive Care...

Prospective validation of the ABCD2 score for patients in the emergency department with transient ischemic attack

by emottawa | Dec 15, 2012 | Journal Club

Journal Club Summary Landmark Series Methodology Score: 4/5 Usefulness Score: 4/5 Perry JJ, Sharma M, Sivilotti ML, Sutherland J, Symington C, Worster A, Émond M, Stotts G, Jin AY, Oczkowski WJ, Sahlas DJ, Murray HE, MacKey A, Verreault...

Apneic oxygenation during prolonged laryngoscopy in obese patients: a randomized, controlled trial of nasal oxygen administration

by emottawa | Nov 23, 2012 | Journal Club

Journal Club Summary Methodology: 3.5/5 Usefulness: 4/5 Ramachandran SK, Cosnowski A, Shanks A, Turner CR. J Clin Anesth. 2010 May;22(3):164-8. PubMed Link This RCT of 30 obese adult male patients receiving either 5L of O2 via NP or no O2 during...

One-Hour Rule-out and Rule-in of Acute Myocardial Infarction Using High-Sensitivity Cardiac Troponin T.

by emottawa | Nov 15, 2012 | Journal Club

Journal Club Summary Methodology: 2.5/5 Usefulness: 3.5/5 Reichlin T, Schindler C, Drexler B, et al. Arch Intern Med. 2012 Sep 10;172(16):1211-8. Abstract Link This study was a prospective, multicenter derivation and internal validation of a...