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C-Reactive Protein Testing to Guide Antibiotic Prescribing for COPD Exacerbations.

C-Reactive Protein Testing to Guide Antibiotic Prescribing for COPD Exacerbations.

by Hans Rosenberg | Apr 6, 2020 | Full Article, Infectious Disease, Journal Club, Respirology

Methodology: 3/5 Usefulness: 2.5/5 Butler CC, et al. N Engl J Med. 2019 Jul 11;381(2):111-120 Editorial: COPD Exacerbations – A Target for Antibiotic Stewardship. Question and Methods: This was a multicenter RCT to determine if POCT CRP testing vs usual care may help...
CRP-guided antibiotic treatment in acute exacerbations of COPD in hospital admissions

CRP-guided antibiotic treatment in acute exacerbations of COPD in hospital admissions

by Hans Rosenberg | Aug 12, 2019 | Infectious Disease, Journal Club, Respirology

Journal Club Summary Methodology Score: 2.5/5 Usefulness Score: 3/5 Prins HJ, et al. Eur Respir J. 2019 May 23;53(5).  Question and Methods: The CATCH Study was a multicentre, randomised, controlled open intervention clinical trial comparing CRP guided antibiotics for...
Outpatient Management of Acute Exacerbations of COPD

Outpatient Management of Acute Exacerbations of COPD

by Alex Mungham, Richard Hoang, Shankar Sethuraman | Jan 17, 2019 | Grand Round Summaries, Respirology

In this post, we review an approach to antibiotics, bronchodilators, and corticosteroids in the outpatient management for acute exacerbations of COPD. COPD – The Basics What is it? An incompletely reversible obstructive lung disease due to airway and/or alveolar...

Short-term vs Conventional Glucocorticoid Therapy in Acute Exacerbations of Chronic Obstructive Pulmonary Disease The REDUCE Randomized Clinical Trial

by emottawa | Sep 30, 2014 | Journal Club

Journal Club Summary Methodology Score: 4/5                 Usefulness Score: 4/5 Leuppi JD, et al. JAMA. 2013 Jun 5;309(21):2223-31. Article Link   This multicenter, double blinded trial demonstrated non-inferiority of a 5-day course of 40mg prednisone versus a...

Short-term vs Conventional Glucocorticoid Therapy in Acute Exacerbations of Chronic Obstructive Pulmonary Disease: the REDUCE randomized clinical trial

by emottawa | Dec 23, 2013 | Journal Club

Journal Club Summary Methodology Score: 4/5                 Usefulness Score: 3.5/5   Leuppi JD, Schuetz P, Bingisser R, Bodmer M, Briel M, Drescher T, et al. JAMA. 2013 Jun 5;309(21):2223-31 Article Link   This multicentre, Swiss-based RCT adds to the literature that...
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World-Class Emergency Medicine: To provide outstanding compassionate emergency care through practice-changing research and innovative medical education. For more about our department, visit us at EMOttawa.

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