Association Between Administration of Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19: A Meta-analysis

Association Between Administration of Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19: A Meta-analysis

Methodology: 4/5 Usefulness: 4/5 WHO Rapid Evidence Appraisal for COVID-19 Therapies (REACT) Working Group, Sterne JAC et al. JAMA. 2020 Oct 6;324(13):1330-1341. Question and Methods: Prospective meta-analysis of 7 RCTs investigating the utility of systemic...
Delayed versus early initiation of renal replacement therapy for severe acute kidney injury: a systematic review and individual patient data meta-analysis of randomised clinical trials

Delayed versus early initiation of renal replacement therapy for severe acute kidney injury: a systematic review and individual patient data meta-analysis of randomised clinical trials

Methodology: 3.5/5 Usefulness: 2/5 Gaudry S, et al. Lancet. 2020 May 9;395(10235):1506-1515. Question and Methods: Gaudry et al performed a systematic review and individual patient data meta-analysis of randomized control trials to compare the benefits of early versus...