by emottawa | Sep 18, 2012 | Journal Club
Journal Club Summary Landmark Series Quant EC, et. al 2009;339:b3354. Methods: 4/5 Usefulness: 4/5 Article Link This high quality meta-analysis demonstrated that the addition of antivirals to steroids did not result in any additional benefit in achieving at least...
by EMOttawa | Sep 12, 2012 | Journal Club, landmark
Journal Club Summary Landmark Series Mayer SA, Brun NC, Begtrup K, Broderick J, Davis S, Diringer MN, et al. N Engl J Med. 2008 May 15;358(20):21 27–37. Article Link This industry sponsored, international multicentre RCT involved 841 patients with acute ICH and found...
by EMOttawa | Sep 3, 2012 | Journal Club, landmark
Journal Club Summary Landmark Series Sprung CL, Annane D, Keh D, Moreno R, Singer M, Freivogel K, et al. N Engl J Med. 2008 Jan.10;358(2):111–24. Article Link This European multicentre RCT compared hydrocortisone to placebo for 499 ICU patients with septic shock and...
by emottawa | Aug 31, 2012 | Journal Club
Journal Club Summary Landmark Series Margaretten ME, Kohlwes J, Moore D, Bent S. JAMA. 2007Apr.4;297(13):1478–88. Article Link This systematic overview from the excellent JAMA series reviewed the relatively weak evidence regarding assessment of patients with...
by EMOttawa | Aug 22, 2012 | Journal Club, landmark
Journal Club Summary Landmark Series Clark E, Plint AC, Correll R, Gaboury I, Passi B. A Pediatrics. 20 07Mar.1;119(3):460–7. Article Link This high quality RCT by local investigators rigorously compared acetaminophen, ibuprofen and codeine analgesics among...
