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A Randomized Controlled Noninferiority Trial of Single Dose of Oral Dexamethasone Versus 5 Days of Oral Prednisone in Acute Adult Asthma

by emottawa | Jun 12, 2017 | Journal Club

Journal Clubs Summary Methodology Score: 3/5  Usefulness Score: 3.5/5 Rehrer MW, et al. Ann Emerg Med. 2016 Nov;68(5):608-613. Abstract Link This single centre, randomized, triple-blinded, control trial did not demonstrate noninferiority of a single dose of...

Adjunct prednisone therapy for patients with community-acquired pneumonia: a multicentre, double-blind, randomised, placebo-controlled trial.

by emottawa | Aug 31, 2015 | Journal Club

Journal Club Summary Methodology Score: 3/5 Usefulness Score: 2/5 Blum CA, Nigro N Briel M, et al. Lancet. 2015 Jan 16. pii: S0140-6736(14)62447-8. Abstract Link This randomized, double-blinded, placebo-controlled trial demonstrated an improved time to ‘clinical...

Short-term vs Conventional Glucocorticoid Therapy in Acute Exacerbations of Chronic Obstructive Pulmonary Disease The REDUCE Randomized Clinical Trial

by emottawa | Sep 30, 2014 | Journal Club

Journal Club Summary Methodology Score: 4/5                 Usefulness Score: 4/5 Leuppi JD, et al. JAMA. 2013 Jun 5;309(21):2223-31. Article Link   This multicenter, double blinded trial demonstrated non-inferiority of a 5-day course of 40mg prednisone versus a...
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