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Vernakalant versus procainamide for rapid cardioversion of patients with acute atrial fibrillation (RAFF4): randomised clinical trial

Vernakalant versus procainamide for rapid cardioversion of patients with acute atrial fibrillation (RAFF4): randomised clinical trial

by Anchaleena Mandal, Christian Vaillancourt | Mar 5, 2026 | Featured

Methodology Score: 4.5/5 Usefulness Score: 4/5 Stiell IG, et al. BMJ. 2025 Nov 11;391:e085632. doi: 10.1136/bmj-2025-085632. Question and Methods: This is a multi-center, open-label, patient randomised trial comparing the effectiveness and safety of cardioversion with...

Randomized comparison of intravenous procainamide vs. intravenous amiodarone for the acute treatment of tolerated wide QRS tachycardia: the PROCAMIO study

by emottawa | Oct 3, 2016 | Journal Club

Journal Club Summary Methodology Score: 2.5/5                 Usefulness Score:  3/5   Ortiz M, et al. Eur Heart J. 2016 Jun 28. pii: ehw230. [Epub ahead of print]   Full Article   This RCT of patients with tolerated wide complex tachycardia found that IV Procainamide...
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