by emottawa | Mar 1, 2016 | Endocrinology, Grand Round Summaries
Steroids have been used in medicine for their immune-modulating effects for decades, but how much of their use is actually evidence based? Here we review the most recent literature for their use in four select presentations often seen in the Emergency...
by emottawa | Nov 3, 2015 | Journal Club
Journal Club Summary Methodology Score: 4/5 Usefulness Score: 3.5/5 Kaukonen KM, Bailey M, Pilcher D, et al. N Engl J Med. 2015 Apr 23;372(17):1629-38. Full Article This retrospective multicenter study found that the use of SIRS criteria to define...
by emottawa | Oct 27, 2014 | Journal Club
Journal Club Summary Landmark Series Methodology Score: 4/5 Usefulness Score: 4/5 ProCESS Investigators N Engl J Med. 2014 May 1;370(18):1683-93. Abstract Link This large multicentre U.S. RCT of 1341 septic patients found no significant differences in mortality...
by emottawa | Sep 22, 2014 | Journal Club
Journal Club Summary Methodology Score: 3.5/5 Usefulness Score: 2.5/5 Caironi P, Tognoni G, et al. the ALBIOS Study Investigators. N Engl J Med. 2014 Mar 18. Abstract Link This was an open-label RCT of 1,800 ICU patients with severe sepsis or septic...
by EMOttawa | Nov 18, 2013 | Journal Club, landmark
Journal Club Summary Landmark Series Methodology Score: 4/5 Usefulness Score: 4.5/5 Perner A, et al.; 6S Trial Group; Scandinavian Critical Care Trials Group. N Engl J Med. 2012 Jul 12;367(2):124-34 Article Link This multi-centre, double-blind,...
