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A randomized trial of protocol-based care for early septic shock

by emottawa | Oct 27, 2014 | Journal Club

Journal Club Summary Landmark Series Methodology Score: 4/5 Usefulness Score:  4/5 ProCESS Investigators  N Engl J Med. 2014 May 1;370(18):1683-93. Abstract Link    This large multicentre U.S. RCT of 1341 septic patients found no significant differences in mortality...

Albumin replacement in patients with severe sepsis or septic shock

by emottawa | Sep 22, 2014 | Journal Club

Journal Club Summary Methodology Score: 3.5/5              Usefulness Score: 2.5/5   Caironi P, Tognoni G, et al. the ALBIOS Study Investigators. N Engl J Med. 2014 Mar 18. Abstract Link   This was an open-label RCT of 1,800 ICU patients with severe sepsis or septic...

Hydroxyethyl Starch 130/0.42 versus Ringer’s Acetate in Severe Sepsis

by EMOttawa | Nov 18, 2013 | Journal Club, landmark

Journal Club Summary Landmark Series Methodology Score: 4/5                 Usefulness Score: 4.5/5   Perner A, et al.; 6S Trial Group; Scandinavian Critical Care Trials Group. N Engl J Med. 2012 Jul 12;367(2):124-34   Article Link   This multi-centre, double-blind,...
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