by emottawa | Mar 2, 2017 | Grand Round Summaries, Resuscitation
Use of the term “sepsis” continues to be controversial. We understand that patients with infection can manifest an immune-mediated systemic response, and are at risk of deterioration, organ dysfunction, and death. At what point in that cascade the patient is termed...
by emottawa | Feb 27, 2017 | Journal Club
Journal Club Summary Methodology Score: 3/5 Usefulness Score: 2.5/5 Keh D, et al. JAMA. 2016 Nov 1;316(17):1775-1785 Abstract Link In this multicenter placebo-controlled double-blind RCT, the authors concluded that in adults with severe sepsis,...
by emottawa | May 24, 2016 | Journal Club
Journal Club Summary Methodology Score: 3.5/5 Usefulness Score: 3 /5 Seymour CW, et al. JAMA. 2016 Feb 23;315(8):762-74 Abstract Link Editorial: New Definitions for Sepsis and Septic Shock Continuing Evolution but With Much Still to Be Done Abraham...
by emottawa | Mar 1, 2016 | Endocrinology, Grand Round Summaries
Steroids have been used in medicine for their immune-modulating effects for decades, but how much of their use is actually evidence based? Here we review the most recent literature for their use in four select presentations often seen in the Emergency...
by emottawa | Nov 3, 2015 | Journal Club
Journal Club Summary Methodology Score: 4/5 Usefulness Score: 3.5/5 Kaukonen KM, Bailey M, Pilcher D, et al. N Engl J Med. 2015 Apr 23;372(17):1629-38. Full Article This retrospective multicenter study found that the use of SIRS criteria to define...