steroids Archives

To ‘Roid or not to ‘Roid: Steroids in the ED!

by emottawa | Mar 1, 2016 | Endocrinology, Grand Round Summaries

Steroids have been used in medicine for their immune-modulating effects for decades, but how much of their use is actually evidence based? Here we review the most recent literature for their use in four select presentations often seen in the Emergency...

Short-term vs Conventional Glucocorticoid Therapy in Acute Exacerbations of Chronic Obstructive Pulmonary Disease The REDUCE Randomized Clinical Trial

by emottawa | Sep 30, 2014 | Journal Club

Journal Club Summary Methodology Score: 4/5 Usefulness Score: 4/5 Leuppi JD, et al. JAMA. 2013 Jun 5;309(21):2223-31. Article Link This multicenter, double blinded trial demonstrated non-inferiority of a 5-day course of 40mg prednisone versus a...

The benefits of steroids versus steroids plus antivirals for treatment of Bell’s palsy: a meta-analysis

by emottawa | Mar 3, 2014 | Journal Club

Journal Club Summary Methodology Score: 3.5/5 Usefulness Score: 3.5/5 Quant EC, Jeste SS, Muni RH, Cape AV, Bhussar MK, Peleg AY. BMJ. 2009 Sep 7;339:b3354. doi: 10.1136/bmj.b3354. Article Link This meta-analysis of randomized controlled trials comparing...

Vasopressin, Steroids, and Epinephrine and Neurologically Favorable Survival After In-Hospital Cardiac Arrest A Randomized Clinical Trial

by emottawa | Jan 13, 2014 | Journal Club

Journal Club Summary Methodology Score: 4/5 Usefulness Score: 2.5/5 Mentzelopoulos SD, et al. JAMA. 2013;310(3):270-279. Article Link This randomized, multi-centered, double blind, placebo controlled trial compared vasopressin, steroids and...

Short-term vs Conventional Glucocorticoid Therapy in Acute Exacerbations of Chronic Obstructive Pulmonary Disease: the REDUCE randomized clinical trial

by emottawa | Dec 23, 2013 | Journal Club

Journal Club Summary Methodology Score: 4/5 Usefulness Score: 3.5/5 Leuppi JD, Schuetz P, Bingisser R, Bodmer M, Briel M, Drescher T, et al. JAMA. 2013 Jun 5;309(21):2223-31 Article Link This multicentre, Swiss-based RCT adds to the literature that...