by Hans Rosenberg | Mar 25, 2019 | Critical Care, Featured, Full Article, Infectious Disease
Journal Club Summary Methodology: 3/5 Usefulness: 3.5/5 Annane D, et al. N Engl J Med. 2018 Mar 1;378(9):809-818. Editorial: A Role for Hydrocortisone Therapy in Septic Shock? Question and Methods: Large multi-center, double-blinded, randomized-controlled trial...
by Alex Mungham, Richard Hoang, Shankar Sethuraman | Jan 17, 2019 | Grand Round Summaries, Respirology
In this post, we review an approach to antibiotics, bronchodilators, and corticosteroids in the outpatient management for acute exacerbations of COPD. COPD – The Basics What is it? An incompletely reversible obstructive lung disease due to airway and/or alveolar...
by emottawa | Aug 15, 2016 | Journal Club
Journal Club Summary Methodology Score: 4/5 Usefulness Score: 3.5/5 Siemieniuk RA, et al. Ann Intern Med. 2015;163(7):519-528. Abstract Link This is a well-done systematic review & meta-analysis elucidating whether corticosteroid therapy...
by emottawa | Mar 1, 2016 | Endocrinology, Grand Round Summaries
Steroids have been used in medicine for their immune-modulating effects for decades, but how much of their use is actually evidence based? Here we review the most recent literature for their use in four select presentations often seen in the Emergency...
by emottawa | Sep 30, 2014 | Journal Club
Journal Club Summary Methodology Score: 4/5 Usefulness Score: 4/5 Leuppi JD, et al. JAMA. 2013 Jun 5;309(21):2223-31. Article Link This multicenter, double blinded trial demonstrated non-inferiority of a 5-day course of 40mg prednisone versus a...