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Efficacy and safety of the novel oral anticoagulants in atrial fibrillation: a systematic review and meta-analysis of the literature

by emottawa | Mar 17, 2014 | Journal Club

Journal Club Summary Methodology Score: 4.5/5              Usefulness Score: 3/5   Dentali F, Riva N, Crowther M, Turpie AG, Lip GY, Ageno W. Circulation. 2012 Nov 13;126(20):2381-91. Article Link   This was a systematic review and meta-analysis of 12 phase II/III...

A new and rapid method for epistaxis treatment using injectable form of tranexamic acid topically: a randomized controlled trial

by emottawa | Mar 10, 2014 | Journal Club

Journal Club Summary Methodology Score: 2/5                  Usefulness Score: 3.5/5 Zahed R, Moharamzadeh P, Alizadeharasi S, Ghasemi A, Saeedi M.Am J Emerg Med.2013 Sep;31(9):1389-92 Abstract Link This single centre, ED based, parallel group randomized control trial...

The benefits of steroids versus steroids plus antivirals for treatment of Bell’s palsy: a meta-analysis

by emottawa | Mar 3, 2014 | Journal Club

Journal Club Summary Methodology Score: 3.5/5               Usefulness Score: 3.5/5 Quant EC, Jeste SS, Muni RH, Cape AV, Bhussar MK, Peleg AY. BMJ. 2009 Sep 7;339:b3354. doi: 10.1136/bmj.b3354. Article Link This meta-analysis of randomized controlled trials comparing...

A 2-Hour Diagnostic Protocol for Possible Cardiac Chest Pain in the Emergency Department

by emottawa | Jan 27, 2014 | Journal Club

Journal Club Summary Methodology Score: 3.5/5                          Usefulness Score: 3/5   Than M, Aldous S, Lord SJ, Goodacre S, Frampton CM, Troughton R, George P, Florkowski CM, Ardagh M, Smyth D, Jardine DL, Peacock WF, Young J, Hamilton G, Deely JM, Cullen L,...

Clinical Decision Rules to Rule Out Subarachnoid Hemorrhage for Acute Headache

by emottawa | Jan 20, 2014 | Journal Club

Journal Club Summary Methodology Score: 4.5/5                          Usefulness Score: 4/5 Perry JJ, Stiell IG, Sivilotti ML, Bullard MJ, Hohl CM, Sutherland J, Émond M, Worster A, Lee JS, Mackey D, Pauls M, Lesiuk H, Symington C, Wells GA. JAMA....

Vasopressin, Steroids, and Epinephrine and Neurologically Favorable Survival After In-Hospital Cardiac Arrest A Randomized Clinical Trial

by emottawa | Jan 13, 2014 | Journal Club

Journal Club Summary Methodology Score: 4/5                 Usefulness Score: 2.5/5   Mentzelopoulos SD, et al. JAMA. 2013;310(3):270-279. Article Link   This randomized, multi-centered, double blind, placebo controlled trial compared vasopressin, steroids and...

Comparison of dopamine and norepinephrine in the treatment of shock.

by EMOttawa | Jan 6, 2014 | Journal Club, landmark

Journal Club Summary Landmark Series Methodology Score: 4/5                 Usefulness Score: 4/5 De Backer D, Biston P, Devriendt J, Madl C, Chochrad D, Aldecoa C, Brasseur A, Defrance P, Gottignies P, Vincent JL; SOAP II Investigators. N Engl J Med. 2010 Mar...

Short-term vs Conventional Glucocorticoid Therapy in Acute Exacerbations of Chronic Obstructive Pulmonary Disease: the REDUCE randomized clinical trial

by emottawa | Dec 23, 2013 | Journal Club

Journal Club Summary Methodology Score: 4/5                 Usefulness Score: 3.5/5   Leuppi JD, Schuetz P, Bingisser R, Bodmer M, Briel M, Drescher T, et al. JAMA. 2013 Jun 5;309(21):2223-31 Article Link   This multicentre, Swiss-based RCT adds to the literature that...

How Do I Perform a Lumbar Puncture and Analyze the Results to Diagnose Bacterial Meningitis?

by emottawa | Dec 16, 2013 | Journal Club

Journal Club Summary Landmark Article Series – UPDATE   Methodology Score: 2.5/5              Usefulness Score: 4/5 Straus SE, Thorpe KE, Holroyd-Leduc J. JAMA. 2006 Oct 25;296(16):2012-22.   Article Link   This overview article from the JAMA Rational Clinical...

A 2-h diagnostic protocol to assess patients with chest pain symptoms in the Asia-Pacific region (ASPECT): a prospective observational validation study

by emottawa | Dec 9, 2013 | Journal Club

Journal Club Summary Methodology Score: 4/5                 Usefulness Score: 3/5   Than M, Cullen L, Reid CM, Lim SH, Aldous S, Ardagh MW, et al. Lancet. 2011 Mar 26;377(9771):1077-84.  Abstract Link    This prospective multicentre cohort study attempted to validate...
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