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Pharmacologic Therapies in Patients With Exacerbation of Chronic Obstructive Pulmonary Disease: A Systematic Review With Meta-analysis.

Pharmacologic Therapies in Patients With Exacerbation of Chronic Obstructive Pulmonary Disease: A Systematic Review With Meta-analysis.

by Hans Rosenberg | Sep 27, 2021 | Journal Club, Respirology

Methodology: 4/5           Usefulness: 4.5/5 Dobler CC, et al. Ann Intern Med. 2020 Mar 17;172(6):413-422.  Questions & Methods: Systematic review of 68 English language RCTs of outpatient/non ICU inpatients with COPDE comparing pharmacologic therapy with placebo/...
Prevalence of Pulmonary Embolism Among Patients With COPD Hospitalized With Acutely Worsening Respiratory Symptoms

Prevalence of Pulmonary Embolism Among Patients With COPD Hospitalized With Acutely Worsening Respiratory Symptoms

by Hans Rosenberg | May 31, 2021 | Journal Club, Respirology, Thrombosis

Methodology: 3/5 Usefulness: 3/5 Couturaud F, et al. JAMA. 2021 Jan 5;325(1):59-68.  Question and Methods: This study used a multicenter, cross-sectional methodology with prospective follow up to determine the rates of PE in 740 COPD patients using the rGeneva score....
Diagnosis and Outpatient Management of Chronic Obstructive Pulmonary Disease: A Review

Diagnosis and Outpatient Management of Chronic Obstructive Pulmonary Disease: A Review

by Hans Rosenberg | Jul 20, 2020 | Journal Club, Respirology

Methodology: 1/5 Usefulness: 2/5 Riley CM, et al. JAMA. 2019 Feb 26;321(8):786-797. Question: Aimed to review and provide practical information regarding the diagnosis and long-term management of patients with COPD in the outpatient setting. Methods: This was a...
C-Reactive Protein Testing to Guide Antibiotic Prescribing for COPD Exacerbations.

C-Reactive Protein Testing to Guide Antibiotic Prescribing for COPD Exacerbations.

by Hans Rosenberg | Apr 6, 2020 | Full Article, Infectious Disease, Journal Club, Respirology

Methodology: 3/5 Usefulness: 2.5/5 Butler CC, et al. N Engl J Med. 2019 Jul 11;381(2):111-120 Editorial: COPD Exacerbations – A Target for Antibiotic Stewardship. Question and Methods: This was a multicenter RCT to determine if POCT CRP testing vs usual care may help...
CRP-guided antibiotic treatment in acute exacerbations of COPD in hospital admissions

CRP-guided antibiotic treatment in acute exacerbations of COPD in hospital admissions

by Hans Rosenberg | Aug 12, 2019 | Infectious Disease, Journal Club, Respirology

Journal Club Summary Methodology Score: 2.5/5 Usefulness Score: 3/5 Prins HJ, et al. Eur Respir J. 2019 May 23;53(5).  Question and Methods: The CATCH Study was a multicentre, randomised, controlled open intervention clinical trial comparing CRP guided antibiotics for...
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