Effect of C-Reactive Protein-Guided Antibiotic Treatment Duration, 7-Day Treatment, or 14-Day Treatment on 30-Day Clinical Failure Rate in Patients with Uncomplicated Gram-Negative Bacteremia: A Randomized Clinical Trial

Effect of C-Reactive Protein-Guided Antibiotic Treatment Duration, 7-Day Treatment, or 14-Day Treatment on 30-Day Clinical Failure Rate in Patients with Uncomplicated Gram-Negative Bacteremia: A Randomized Clinical Trial

by , | Oct 25, 2021 | Full Article, Infectious Disease, Journal Club

Methodology: 1/5           Usefulness: 1/5 von Dach E, et al. JAMA. 2020 Jun 2;323(21):2160-2169. doi: 10.1001/jama.2020.6348. Question and Methods: In a multi-center, noninferiority, randomized, double-blinded clinical trial, the authors compared the rates of...
Blood Culture Results Before and After Antimicrobial Administration in Patients With Severe Manifestations of Sepsis: A Diagnostic Study

Blood Culture Results Before and After Antimicrobial Administration in Patients With Severe Manifestations of Sepsis: A Diagnostic Study

by | Dec 7, 2020 | Critical Care, Featured, Infectious Disease, Journal Club

Methodology: 3.5/5 Usefulness: 3.5/5 Ann Intern Med. 2019 Oct 15;171(8):547-554. Cheng MP, et al. Question and Methods: Multi-center diagnostic study that investigated the sensitivity of post-antimicrobial blood cultures compared to pre-antimicrobial blood cultures in...