Journal Club Summary Alam N, et al. Lancet Respir Med. 2018 Jan;6(1):40-50. Question and Methods: The authors of this nation-wide open-label RCT studied the mortality effect of pre-hospital antibiotics on febrile patients with one other non-laboratory SIRS criteria by comparing pre-hospital usual care with IV fluids and oxygen to theRead More →
Journal Club Summary Methodology: 3.5/5 Usefulness: 3/5 Peacock WF, et al. JAMA Cardiol. 2017 Dec 13 EDITORIAL: The Wait for High-Sensitivity Troponin Is Over-Proceed Cautiously Korley FK. JAMA Cardiol. 2017 Dec 13 Question and Methods: This prospective, observational, multicenter study evaluated if a negative hsTnt assay at 0h and 3h post EDRead More →
Methodology Score: 3.5/5 Usefulness Score: 3/5 Semler MW, et al. Chest. 2017 Oct;152(4):712-722. Editorial: Should the Ramped Position Be “Sniffed at” in the ICU? Scott JA, et al. Chest. 2017 Oct;152(4):693-694. Question and Methods: Multicenter, randomized, unblinded, trial of 260 ICU patients comparing the ramped vs sniffing position for intubations performed by criticalRead More →
Journal Club Summary Methodology Score: 3.5/5 Usefulness Score: 3.5/5 Cournoyer A, et al. Acad Emerg Med. 2017 Sep;24(9):1100-1109. Question and Methods: Retrospective observational cohort study to evaluate if the addition ACLS to BLS during EMS management for Out-of-Hospital cardiac arrest – OHCA (and for a predefined subgroup of potential ECMO candidates) improve ratesRead More →
Journal Club Summary Dewey M, et al. BMJ. 2016 Oct 24;355:i5441. Methodology: 2.5/5 Usefulness: 2.5/5 Question and Methods: Prospective single center RCT to determine whether patients with intermediate probability of CAD and atypical chest pain/angina should undergo cardiac CT or coronary angiography. Findings: The study found no difference in major procedural complications withinRead More →
Journal Club Summary Methodology Score: 3.5/5 Usefulness Score: 3.5/5 Question and Methods: This meta-analysis included prospective studies to assess the ability of a single negative hs-cTnT and non-ischemic ECG to identify patients at low risk for AMI. Findings: The results of 11 studies were pooled, resulting in a pooled sensitivityRead More →
I wanted to share with you a brief history on how our Department of Emergency Medicine (DEM) at the University of Ottawa developed and evolved from what we called our Web 2.0 program to our current official Digital Scholarship and Knowledge Dissemination program. As far as I know, it’s oneRead More →
Journal Club Summary Methodology Score: 3/5 Usefulness Score: 2.5/5 Question and Methods: This tertiary-care centre, placebo controlled RCT examined whether nasally inhaling isopropyl alcohol provides better nausea relief than normal saline. Findings: At 10 mins, inhaled isopropyl alcohol offers increased nausea relief compared to normal saline (effect size of 3)Read More →
Journal Club Summary Hofmann R, et al. N Engl J Med. 2017 Sep 28;377(13):1240-1249. Methodology Score: 4/5 Usefulness Score: 4/5 Question and Methods: This large, registry-based RCT evaluated the effect of oxygen on patient-centered clinical outcomes for normoxic MI patients. Findings: There were no differences at 365 days or 30Read More →
Journal Club Summary Khanna A, et al. N Engl J Med. 2017 Aug 3;377(5):419-430. Abstract Link EDITORIAL: Angiotensin II for the Treatment of Vasodilatory Shock – Promise and Caution. Dellinger RP, et al. N Engl J Med. 2017 Aug 3;377(5):486-487. Methodology Score: 4/5 Usefulness Score: 3.5/5 Question and Methods: International multicenter placebo-controlled RCTRead More →