
Out-of-Hospital Intranasal Ketamine as an Adjunct to Fentanyl for the Treatment of Acute Traumatic Pain: A Randomized Clinical Trial
Methodology: 4/5 Usefulness: 2/5 McMullan JT, et al. Ann Emerg Med. 2024 Oct;84(4):363-373. doi: 10.1016/j.annemergmed.2024.04.018. Question and Methods: This... Read more.

Validation of the Hospital for Sick Children Algorithm for Discriminating Bacteremia From Contaminants in Children With a Preliminary Positive Blood Culture
Methodology: 3.5/5 Usefulness: 2/5 Gravel J, et al. Ann Emerg Med. 2024 Nov;84(5):490-499. doi: 10.1016/j.annemergmed.2024.05.005. Question and Methods: The authors... Read more.

Derivation of the Falls Decision Rule to exclude intracranial bleeding without head CT in older adults who have fallen
Methodology: 3.5/5 Usefulness: 3.5/5 CMAJ. 2023 Dec 3;195(47):E1614-E1621. de Wit K, et al. doi: 10.1503/cmaj.230634. Question and Methods: The Falls Decision... Read more.

Restrictive or Liberal Transfusion Strategy in Myocardial Infarction and Anemia
Methodology: 4/5 Usefulness: 3.5/5 Carson JL, et al. N Engl J Med. 2023 Dec 28;389(26):2446-2456. doi: 10.1056/NEJMoa2307983. Questions and methods: This multicenter,... Read more.

Early versus Later Anticoagulation for Stroke with Atrial Fibrillation
Methodology: 3/5 Usefulness: 2/5 Fischer U, et al. N Engl J Med. 2023 Jun 29;388(26):2411-2421. Question and Methods: RCT at 103 sites to compare outcomes at 30... Read more.

Effect of Bougie Use on First-Attempt Success in Tracheal Intubations: A Systematic Review and Meta-Analysis
Methodology: 4/5 Usefulness: 3/5 von Hellmann R, et al. Ann Emerg Med. 2024 Feb;83(2):132-144. Question and Methods: Systematic review of 18 studies (12 RCT) of... Read more.

Emergency Department Resuscitative Endovascular Balloon Occlusion of the Aorta in Trauma Patients With Exsanguinating Hemorrhage: The UK-REBOA Randomized Clinical Trial
Methodology: 2/5 Usefulness: 2/5 Jansen JO, et al. JAMA. 2023 Oct 12:e2320850. Editorial: Contemporary Adjuncts to Hemorrhage Control. Question and Methods: Multi-center... Read more.

Early and Empirical High-Dose Cryoprecipitate for Hemorrhage After Traumatic Injury: The CRYOSTAT-2 Randomized Clinical Trial
Methodology: 3.5/5 Usefulness: 4/5 Davenport R, et al. JAMA. 2023 Oct 12:e2321019. Editorial: Contemporary Adjuncts to Hemorrhage Control. Question and Methods:... Read more.

Diuretic vs. placebo in intermediate-risk acute pulmonary embolism: a randomized clinical trial
Methodology: 2/5 Usefulness: 1/5 Lim P, et al. Eur Heart J Acute Cardiovasc Care. 2022 Jan 12;11(1):2-9. Question and Methods: Does diuresis with single-dose IV... Read more.

Reduction of urea test ordering in the emergency department: multicomponent intervention including education, electronic ordering, and data feedback
Methodology: 2.5/5 Usefulness: 2/5 Mathura P, et al. CJEM. 2022 Sep;24(6):636-640. Editorial: When evidence-based medicine and quality improvement collide. Question... Read more.