Restrictive or Liberal Transfusion Strategy in Myocardial Infarction and Anemia
Methodology: 4/5 Usefulness: 3.5/5 Carson JL, et al. N Engl J Med. 2023 Dec 28;389(26):2446-2456. doi: 10.1056/NEJMoa2307983. Questions and methods: This mult... Read more.
Early versus Later Anticoagulation for Stroke with Atrial Fibrillation
Methodology: 3/5 Usefulness: 2/5 Fischer U, et al. N Engl J Med. 2023 Jun 29;388(26):2411-2421. Question and Methods: RCT at 103 sites to compare outcomes at ... Read more.
Effect of Bougie Use on First-Attempt Success in Tracheal Intubations: A Systematic Review and Meta-Analysis
Methodology: 4/5 Usefulness: 3/5 von Hellmann R, et al. Ann Emerg Med. 2024 Feb;83(2):132-144. Question and Methods: Systematic review of 18 studies (12 RCT) ... Read more.
Emergency Department Resuscitative Endovascular Balloon Occlusion of the Aorta in Trauma Patients With Exsanguinating Hemorrhage: The UK-REBOA Randomized Clinical Trial
Methodology: 2/5 Usefulness: 2/5 Jansen JO, et al. JAMA. 2023 Oct 12:e2320850. Editorial: Contemporary Adjuncts to Hemorrhage Control. Question and Methods: ... Read more.
Early and Empirical High-Dose Cryoprecipitate for Hemorrhage After Traumatic Injury: The CRYOSTAT-2 Randomized Clinical Trial
Methodology: 3.5/5 Usefulness: 4/5 Davenport R, et al. JAMA. 2023 Oct 12:e2321019. Editorial: Contemporary Adjuncts to Hemorrhage Control. Question and Method... Read more.
Diuretic vs. placebo in intermediate-risk acute pulmonary embolism: a randomized clinical trial
Methodology: 2/5 Usefulness: 1/5 Lim P, et al. Eur Heart J Acute Cardiovasc Care. 2022 Jan 12;11(1):2-9. Question and Methods: Does diuresis with single-dose IV... Read more.
Reduction of urea test ordering in the emergency department: multicomponent intervention including education, electronic ordering, and data feedback
Methodology: 2.5/5 Usefulness: 2/5 Mathura P, et al. CJEM. 2022 Sep;24(6):636-640. Editorial: When evidence-based medicine and quality improvement collide. Ques... Read more.
Risk of Traumatic Brain Injuries in Infants Younger than 3 Months With Minor Blunt Head Trauma
Methodology: 3/5 Usefulness: 3.5/5 Abid Z, et al. Ann Emerg Med. 2021 Sep;78(3):321-330.e1. Question and Methods: The study assessed the risk of brain injurie... Read more.
Dexamethasone and ketorolac compare with ketorolac alone in acute renal colic: A randomized clinical trial
Methodology: 2.5/5 Usefulness: 2.5/5 Razi A, et al. Am J Emerg Med. 2022 Aug;58:245-250. Question and Methods: This single-center, RCT of 120 patients with ... Read more.
High-Sensitivity Cardiac Troponin on Presentation to Rule Out Myocardial Infarction: A Stepped-Wedge Cluster Randomized Controlled Trial
Methodology: 3.5/5 Usefulness: 3.5/5 Anand A, et al. Circulation. 2021 Jun 8;143(23):2214-2224. Raising the Bar for Clinical Cardiac Troponin Research Studies... Read more.