Efficacy and safety of intravenous nerinetide initiated by paramedics in the field for acute cerebral ischaemia within 3 h of symptom onset (FRONTIER): a phase 2, multicentre, randomised, double-blind, placebo-controlled study

Efficacy and safety of intravenous nerinetide initiated by paramedics in the field for acute cerebral ischaemia within 3 h of symptom onset (FRONTIER): a phase 2, multicentre, randomised, double-blind, placebo-controlled study

Methodology: 4/5 Usefulness: 4/5 Christenson J, et al. Lancet. 2025 Feb 15;405(10478):571-582. doi: 10.1016/S0140-6736(25)00193-X.  Question and Methods: Double-blind, placebo-controlled RCT to determine if prehospital administration of nerinetide for suspected acute...
Ottawa Handbook of Emergency Medicine – 6th Edition!

Ottawa Handbook of Emergency Medicine – 6th Edition!

We’re excited to announce the release of the 6th edition of the Ottawa Handbook of Emergency Medicine – a peer-reviewed, point-of-care resource created to support you in the emergency department. With new and improved content, this edition continues to build on the...