Expedited transfer to a cardiac arrest centre for non-ST-elevation out-of-hospital cardiac arrest (ARREST): a UK prospective, multicentre, parallel, randomised clinical trial
Methodology: 5/5 Usefulness: 3/5 Patterson T, et al. Lancet. 2023 Oct 14;402(10410):1329-1337. Patients who sustain an out-of-hospital cardiac arrest without si... Read more.
Extracorporeal Life Support in Infarct-Related Cardiogenic Shock
Methodology: 4/5 Usefulness: 3.5/5 Thiele H, et al. N Engl J Med. 2023 Oct 5;389(14):1286-1297. Editorial: Routine Early ECLS in Infarct-Related Cardiogenic Sho... Read more.
Randomized Trial Comparing Low- vs High-Dose IV Dexamethasone for Patients With Moderate to Severe Migraine
Methodology: 3.5/5 Usefulness: 4/5 Friedman BW, et al. Neurology. 2023 Oct 3;101(14):e1448-e1454. Question and Methods: This double-blinded RCT of 209 patien... Read more.
Modification of the GRACE Risk Score for Risk Prediction in Patients With Acute Coronary Syndromes
Methodology: 3/5 Usefulness: 1/5 Georgiopoulos G, et al. JAMA Cardiol. 2023 Oct 1;8(10):946-956 Question: Does the modified GRACE score incorporating continuous... Read more.
The third Intensive Care Bundle with Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial (INTERACT3): an international, stepped wedge cluster randomised controlled trial
Methodology: 4/5 Usefulness: 4/5 Ma L, et al. Lancet 2023 Jul 1;402(10395):27-40. Question and Methods: Do 6 month outcomes improve after implementation of a go... Read more.
Video versus Direct Laryngoscopy for Tracheal Intubation of Critically Ill Adults
Methodology: 4/5 Usefulness: 3.5/5 Prekker ME et al. N Engl J Med. 2023 Aug 3;389(5):418-429. Question and Methods: Authors aimed to determine if video laryn... Read more.
Implementation of a standardized pregnancy screening process to address gender disparities in radiology turn-around-time and ED length of stay
Methodology: 1.5/5 Usefulness: 1.5/5 Loke DE, et al. CJEM. 2022 Mar;24(2):206-213. Question and Methods: Trying to quantify gender disparities in CT turnaround ... Read more.
Efficacy and Safety of Early Administration of 4-Factor Prothrombin Complex Concentrate in Patients With Trauma at Risk of Massive Transfusion: The PROCOAG Randomized Clinical Trial
Methodology: 4/5 Usefulness: 3.5/5 Bouzat P, et al. JAMA. 2023 Mar 21:e234080. doi: 10.1001/jama.2023.4080. Question and Methods: This double-blind, randomi... Read more.
Quality initiative to improve emergency department sepsis bundle compliance through utilisation of an electronic health record tool
Methodology: 2/5 Usefulness: 3/5 Warstadt NM, et al. BMJ Open Qual. 2022 Jan;11(1):e001624. Questions and Methods: Using a cohort and QI approach, to demonstrat... Read more.
Safely reducing abdominal/pelvic computed tomography imaging in pediatric trauma: a quality improvement initiative
Methodology: 4.5/5 Usefulness: 5/5 Beno S, al. CJEM. 2022 Aug;24(5):535-543. Editorial: Reducing overuse of CT imaging in pediatric trauma: a model example of... Read more.