by Sam Wilson, Venkatesh Thiruganasambandamoorthy | Jun 1, 2026 | Critical Care, Journal Club, Resuscitation
Personalized Hemodynamic Resuscitation Targeting Capillary Refill Time in Early Septic Shock: The ANDROMEDA-SHOCK-2 Randomized Clinical Trial. Hernandez G, ANDROMEDA-SHOCK-2 Investigators for the ANDROMEDA Research Network JAMA. 2025 Oct 29:e2520402. doi:...
by Grace Northrop | May 28, 2026 | Featured
Acute Liver Failure (ALF) is rare, with an estimated incidence of 1–6 cases per million per year in Western countries¹². Despite its rarity, it carries significant morbidity and mortality¹. ALF most often affects previously healthy adults in their 30s; in North...
by Stephen Hale, Venkatesh Thiruganasambandamoorthy | May 27, 2026 | Journal Club, Resuscitation
A Randomized Trial of Shared Decision-Making in Code Status Discussions Becker C, et al. NEJM Evid. 2025 May;4(5):EVIDoa2400422. doi: 10.1056/EVIDoa2400422. Methodology: 3.5/5 Usefulness: 3.5/5 Question and Methods: This multi-centre cluster-RCT...
by Meehan Andrew, Venkatesh Thiruganasambandamoorthy | May 25, 2026 | Journal Club, Neurology
Tenecteplase versus standard medical treatment for basilar artery occlusion within 24 h (TRACE-5): a multicentre, prospective, randomised, open-label, blinded-endpoint, superiority, phase 3 trial Xiong Y, Et al. Lancet. 2026 Feb 21;407(10530):763-772. doi:...
by Rebecca Seliga | May 21, 2026 | Critical Care, Featured, Grand Round Summaries, Resuscitation, Toxicology
In the ED we are certainly no stranger to seeing alcohol use disorder, its complications, and alcohol withdrawal. Every day in Canada, there are approximately 269 hospitalizations directly attributable to alcohol. This is more than admissions for acute MI. As the...
