by Kevin Guo, Hans Rosenberg, Krishan Yadav | May 3, 2023 | Critical Care, Featured, Infectious Disease, Journal Club, Resuscitation
Methodology: 4/5 Usefulness: 4/5 Dequin PF, et al. N Engl J Med. 2023 Mar 21. doi: 10.1056/NEJMoa2215145. Question and Methods: Pneumosepsis can lead to pulmonary and systemic inflammation that can increase risk of organ failure and death. The authors attempted to...
by Hans Rosenberg | Feb 17, 2020 | Infectious Disease, Journal Club, Respirology
Methodology: 4/5 Usefulness: 2/5 Alexander E., et al. JAMA. 2019 Sep 27. doi: 10.1001/jama.2019.15468. Editorial: Lefamulin-A New Antibiotic for Community-Acquired Pneumonia. Question and Methods: LEAP-2 was a phase 3, double-blinded RCT to determine non-inferiority...
by emottawa | Mar 1, 2016 | Endocrinology, Grand Round Summaries
Steroids have been used in medicine for their immune-modulating effects for decades, but how much of their use is actually evidence based? Here we review the most recent literature for their use in four select presentations often seen in the Emergency...