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Mortality and morbidity in acutely ill adults treated with liberal versus conservative oxygen therapy (IOTA): a systematic review and meta-analysis

Mortality and morbidity in acutely ill adults treated with liberal versus conservative oxygen therapy (IOTA): a systematic review and meta-analysis

by Hans Rosenberg | Jul 2, 2018 | Journal Club

Journal Club Summary Methodology: 4/5 Usefulness: 4/5 Chu DK, et al. Lancet. 2018 Apr 28;391(10131):1693-1705. Question & Methods: The authors wanted to summarize the best available evidence of RCTs to guide rational use of O2 therapy. Findings: Their review of...
Immobilization in external rotation combined with abduction reduces the risk of recurrence after primary anterior shoulder dislocation

Immobilization in external rotation combined with abduction reduces the risk of recurrence after primary anterior shoulder dislocation

by Hans Rosenberg | Jun 25, 2018 | Journal Club, Orthopedics

Methodology: 3.5/5 Usefulness: 2.5/5 Heidari K. et al. J Shoulder Elbow Surg. 2014 Jun;23(6):759-66. Journal Club Bottom Line Question & Methods: Can abduction and external rotation (AbER) immobilization after primary anterior shoulder dislocation reduce rates of...
Diagnostic Accuracy of the Aortic Dissection Detection Risk Score Plus D-Dimer for Acute Aortic Syndromes: The ADvISED Prospective Multicenter Study

Diagnostic Accuracy of the Aortic Dissection Detection Risk Score Plus D-Dimer for Acute Aortic Syndromes: The ADvISED Prospective Multicenter Study

by Hans Rosenberg | Jun 18, 2018 | Cardiology, Journal Club

Methodology Score: 3/5 Usefulness Score: 3/5 Nazerian P, et al. Circulation. 2018 Jan 16;137(3):250-258.  Editorial – Biomarker-Assisted Diagnosis of Acute Aortic Dissection. Question: The ADvISED trial was an International Multicenter prospective observational...
Adjunctive Glucocorticoid Therapy in Patients with Septic Shock

Adjunctive Glucocorticoid Therapy in Patients with Septic Shock

by Hans Rosenberg | Jun 11, 2018 | Critical Care, Endocrinology, Journal Club, Resuscitation

Methodology Score: 4/5 Usefulness Score: 3/5 Venkatesh B, et al. N Engl J Med. 2018 Jan 19. Journal Club Bottom Line Question/Methods: This was a international, pragmatic, double-blind, randomized, controlled trial comparing hydrocortisone as continuous infusion to...
DEFUSE-3: Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging

DEFUSE-3: Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging

by Hans Rosenberg | Jun 4, 2018 | Featured, Journal Club, landmark, Neurology

Methodology: 3.5/5 Usefulness: 4/5 Albers GW, et al. N Engl J Med. 2018 Jan 24. Journal Club Bottom Line Question/Methods: This was a multicentre, prospective, randomized, open label, blinded outcome trial comparing thrombectomy + medical therapy vs medical therapy...
Impact of two-step urine culture ordering in the emergency department: a time series analysis

Impact of two-step urine culture ordering in the emergency department: a time series analysis

by Hans Rosenberg | May 14, 2018 | Journal Club, Quality Improvement, Urology

Journal Club Summary Methodology Score: 4/5                   Usefulness Score: 4/5 Stagg A, et al. BMJ Qual Saf. 2018 Feb;27(2):140-147.  Question and Methods: This QI time-series analysis assessed the efficacy, safety and costs of a 2-step urine culture (UC)...
Prehospital antibiotics in the ambulance for sepsis: a multicentre, open label, randomised trial

Prehospital antibiotics in the ambulance for sepsis: a multicentre, open label, randomised trial

by Hans Rosenberg | Apr 16, 2018 | Infectious Disease, Journal Club

Journal Club Summary Alam N, et al. Lancet Respir Med. 2018 Jan;6(1):40-50.  Question and Methods: The authors of this nation-wide open-label RCT studied the mortality effect of pre-hospital antibiotics on febrile patients with one other non-laboratory SIRS criteria...
Efficacy of High-Sensitivity Troponin T in Identifying Very-Low-Risk Patients With Possible Acute Coronary Syndrome.

Efficacy of High-Sensitivity Troponin T in Identifying Very-Low-Risk Patients With Possible Acute Coronary Syndrome.

by Hans Rosenberg | Apr 9, 2018 | Cardiology, Journal Club

Journal Club Summary Methodology: 3.5/5           Usefulness: 3/5 Peacock WF, et al. JAMA Cardiol. 2017 Dec 13 EDITORIAL: The Wait for High-Sensitivity Troponin Is Over-Proceed Cautiously Korley FK. JAMA Cardiol. 2017 Dec 13 Question and Methods: This prospective,...
A Multicenter, Randomized Trial of Ramped Position vs Sniffing Position During Endotracheal Intubation of Critically Ill Adults

A Multicenter, Randomized Trial of Ramped Position vs Sniffing Position During Endotracheal Intubation of Critically Ill Adults

by Hans Rosenberg | Mar 26, 2018 | Anesthesiology, Journal Club, Resuscitation

Methodology Score: 3.5/5                Usefulness Score: 3/5 Semler MW, et al. Chest. 2017 Oct;152(4):712-722. Editorial: Should the Ramped Position Be “Sniffed at” in the ICU? Scott JA, et al. Chest. 2017 Oct;152(4):693-694. Question and Methods:...
Prehospital Advanced Cardiac Life Support for Out-of-hospital Cardiac Arrest: A Cohort Study.

Prehospital Advanced Cardiac Life Support for Out-of-hospital Cardiac Arrest: A Cohort Study.

by Hans Rosenberg | Mar 19, 2018 | Cardiology, Full Article, Journal Club, Resuscitation

Journal Club Summary Methodology Score: 3.5/5 Usefulness Score: 3.5/5 Cournoyer A, et al. Acad Emerg Med. 2017 Sep;24(9):1100-1109. Question and Methods: Retrospective observational cohort study to evaluate if the addition ACLS to BLS during EMS management for...
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