by Hans Rosenberg | Dec 17, 2018 | Featured, Journal Club, Thrombosis
Journal Club Summary Methodology: 4/5 Usefulness: 4/5 Kent AP, et al. J Am Coll Cardiol. 2018 Jul 17;72(3):255-267 Question and Methods: This was a post hoc analysis of the RE-LY trial examining the risk of NSAID use in patients receiving oral anticoagulation (OAC)...
by Hans Rosenberg | Nov 26, 2018 | Journal Club, Neurology
Journal Club Summary Methodology Score: 4/5 Usefulness Score: 5/5 Nogueira RG, et al. N Engl J Med. 2018 Jan 4;378(1):11-21 Editorial: A New DAWN for Imaging-Based Selection in the Treatment of Acute Stroke. Questions and Methods: DAWN was an open-label multi-centre...
by Hans Rosenberg | Nov 19, 2018 | Journal Club, landmark, Neurology
Journal Club Summary Methodology Score: 3.5/5 Usefulness Score: 4/5 Johnston SC, et al. N Engl J Med. 2018 Jul 19;379(3):215-225 Editorial: Antiplatelet Therapy after Ischemic Stroke or TIA. Question and Methods: This randomized, double-blind trial evaluated ASA +...
by Hans Rosenberg | Nov 12, 2018 | Critical Care, Endocrinology, Journal Club
Journal Club Summary Methodology: 4/5 Usefulness: 4/5 Kuppermann N, et al. N Engl J Med. 2018 Jun 14;378(24):2275-2287. Editorial: Fluid Composition, Infusion Rate, and Brain Injury in Diabetic Ketoacidosis. Question and Methods: 13 centre RCT with four arms to...
by Hans Rosenberg | Nov 5, 2018 | Anesthesiology, Journal Club, landmark
Journal Club Summary Methodology Score: 4/5 Usefulness Score: 5/5 Nath S, et al. Lancet. 2018 Mar 24;391(10126):1197-1204 Question and Methods: This meta-analysis sought to determine, in lumbar punctures, whether atraumatic or conventional (traumatic) spinal needles...
by Hans Rosenberg | Oct 29, 2018 | cardiac arrest, Cardiology, Critical Care, Journal Club, Resuscitation
Journal Club Summary: A Randomized Trial of Epinephrine in Out-of-Hospital Cardiac Arrest Methodology Score: 4/5 Usefulness Score: 3.5/5 Perkins GD, et al N Engl J Med. 2018 Jul 18. Editorial: Testing Epinephrine for Out-of-Hospital Cardiac Arrest. Callaway CW, et...
by Hans Rosenberg | Oct 22, 2018 | Journal Club, Resuscitation, Trauma
Journal Club Summary Methodology: 3.5/5 Usefulness: 3.5/5 Moore HB, et al. Lancet. 2018 Jul 28;392(10144):283-291. Editorial: No gains with plasma-first resuscitation in urban settings? Question and Methods: Use of prehospital plasma in patients with...
by Hans Rosenberg | Jul 16, 2018 | Airway, Anesthesiology, Critical Care, Journal Club
Journal Club Summary Methodology Score: 4/5 Usefulness Score: 3/5 Driver BE, et al. JAMA. 2018 May 16. doi: 10.1001/jama.2018.6496. Question/Methods: This single-centre, randomized clinical trial enrolled 757 patients to compare first-attempt intubation success...
by Hans Rosenberg | Jul 9, 2018 | Journal Club, Pediatrics, Trauma
Methodology Score: 3.5/5 Usefulness Score: 4/5 Babl FE, et al. Lancet. 2017 Jun 17;389(10087):2393-2402. Question and Methods: This prospective observational study sought to externally validate and subsequently compare the relative performance of the PECARN, CATCH,...
by Hans Rosenberg | Jul 2, 2018 | Journal Club
Journal Club Summary Methodology: 4/5 Usefulness: 4/5 Chu DK, et al. Lancet. 2018 Apr 28;391(10131):1693-1705. Question & Methods: The authors wanted to summarize the best available evidence of RCTs to guide rational use of O2 therapy. Findings: Their review of...