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Ticagrelor and Aspirin or Aspirin Alone in Acute Ischemic Stroke or TIA.

Ticagrelor and Aspirin or Aspirin Alone in Acute Ischemic Stroke or TIA.

by Hans Rosenberg | Nov 9, 2020 | Journal Club, Neurology

Methodology: 2/5 Usefulness: 2/5 Johnston SC, et al. N Engl J Med. 2020 Jul 16;383(3):207-217. Question and Methods: Multicentre, double-blind RCT of ASA vs Ticagrelor-ASA among 11016 patients with high-risk TIA or minor stroke for prevention of stroke/death within 30...
The Status on Status: Management of Status Epilepticus

The Status on Status: Management of Status Epilepticus

by Evelyn Tran | Jul 16, 2020 | Featured, Grand Round Summaries, Neurology

Status epilepticus (SE) is considered one of the most common neurological emergencies with an estimated incidence of 20 cases/100,000 people worldwide. Just the facts The distribution is bimodal, peaking in patients <1 and >60 years old.  In children, the cause...
What a headache: Updates on Migraine Management

What a headache: Updates on Migraine Management

by Maeghan Fu | Jul 9, 2020 | Featured, Grand Round Summaries, Neurology, Neurology

Migraine headaches are not a benign disease – they have a significant impact on quality of life, ability to function, and pose a considerable economic and societal burden. Prevalence tends to peak during peoples’ period of highest productivity.  According...
Randomized Trial of Three Anticonvulsant Medications for Status Epilepticus

Randomized Trial of Three Anticonvulsant Medications for Status Epilepticus

by Hans Rosenberg | Mar 2, 2020 | Journal Club, Neurology, Pediatrics

Methodology Score: 4/5 Usefulness Score: 3.5/5 Kapur J et al. N Engl J Med. 2019 Nov 28;381(22):2103-2113.  Question and Methods: A multicenter, randomized, blinded, comparative-effectiveness trial to determine the efficacy and safety of fosphenytoin, valproic acid...
Diagnosis of Elevated Intracranial Pressure in Critically Ill Patients

Diagnosis of Elevated Intracranial Pressure in Critically Ill Patients

by Shannon Fernando | Sep 26, 2019 | Featured, Neurology

In the Emergency Department (ED) and Intensive Care Unit (ICU), we often encounter patients with brain injury. This includes patients with traumatic brain injury (TBI), subarachnoid hemorrhage (SAH), and intracerebral hemorrhage (ICH), among others [1]. In the ED and...
Thrombolysis Guided by Perfusion Imaging up to 9 Hours after Onset of Stroke

Thrombolysis Guided by Perfusion Imaging up to 9 Hours after Onset of Stroke

by Hans Rosenberg | Jul 29, 2019 | Journal Club, Neurology

Journal Club Summary Methodology: 3.5/5 Usefulness: 2.5/5 Ma H, et al N Engl J Med. 2019 May 9;380(19):1795-1803 Editorial: Image-Guided Intravenous Alteplase for Stroke – Shattering a Time Window.  Question and Methods: This was an international, multicenter,...
Concussion: Complications and Public Safety (Part 3)

Concussion: Complications and Public Safety (Part 3)

by Erica Lee | Jul 18, 2019 | Grand Round Summaries, Neurology, Trauma

In the final post of this 3-part series on concussions, Dr. Erica Lee discusses how to recognize and manage post-concussion complications, and hopes to raise awareness on the legislation and public health burden around concussions. If you haven’t already, please...
Concussion: Complications and Public Safety (Part 3)

Concussion: Inside the Emergency Department (Part 2)

by Erica Lee | Jul 11, 2019 | Grand Round Summaries, Neurology, Trauma

Welcome to Part 2 of our series on concussions. In this post, Dr. Erica Lee reviews how to make the diagnosis of concussion and manage these patients in the ED. You can review Part 1 of the series for an up-to-date definition of a concussion and Part 3 for a...
Concussion: Inside the Head (Part 1)

Concussion: Inside the Head (Part 1)

by Erica Lee | Jun 27, 2019 | Grand Round Summaries, Neurology, Trauma

Head injuries are commonly seen in the emergency department and a large group of these patients will subsequently be diagnosed with a concussion. In this three-part series, we will summarize the most up to date definition of a concussion (Part 1), review how to make...
An Update on the ED Management of Acute Ischemic Stroke and TIA

An Update on the ED Management of Acute Ischemic Stroke and TIA

by Michael Hale | Jun 13, 2019 | Grand Round Summaries, Neurology

Ischemic stroke is one of Canada’s leading causes of morbidity and mortality. Over the last 30 years, we have observed rapid advances concerning how we identify, respond to, and treat patients with acute ischemic stroke. Because this topic is so vast, the focus of...
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