by emottawa | Oct 4, 2012 | Journal Club
Journal Club Summary Methodology Score: 3/5 Usefulness Score: 3/5 Douma RA, Mos IC, et al. Prometheus Study Group. Article Link This European study directly compared four clinical decision rules in combination with d-dimer testing to exclude PE without the need for...
by emottawa | Sep 24, 2012 | Journal Club
Journal Club Summary Methodology Score: 3/5 Usefulness Score: 2.5/5 Galvagno SM Jr, Haut ER, Zafar SN, Millin MG, Efron DT, Koenig GJ Jr, Baker SP, Bowman SM, Pronovost PJ, Haider AH. JAMA 2012 Apr 18;307(15):1602-10. Article Link This...
by emottawa | Sep 18, 2012 | Journal Club
Journal Club Summary Landmark Series Quant EC, et. al 2009;339:b3354. Methods: 4/5 Usefulness: 4/5 Article Link This high quality meta-analysis demonstrated that the addition of antivirals to steroids did not result in any additional benefit in achieving at least...
by EMOttawa | Sep 12, 2012 | Journal Club, landmark
Journal Club Summary Landmark Series Mayer SA, Brun NC, Begtrup K, Broderick J, Davis S, Diringer MN, et al. N Engl J Med. 2008 May 15;358(20):21 27–37. Article Link This industry sponsored, international multicentre RCT involved 841 patients with acute ICH and found...
by EMOttawa | Sep 3, 2012 | Journal Club, landmark
Journal Club Summary Landmark Series Sprung CL, Annane D, Keh D, Moreno R, Singer M, Freivogel K, et al. N Engl J Med. 2008 Jan.10;358(2):111–24. Article Link This European multicentre RCT compared hydrocortisone to placebo for 499 ICU patients with septic shock and...
by emottawa | Aug 31, 2012 | Journal Club
Journal Club Summary Landmark Series Margaretten ME, Kohlwes J, Moore D, Bent S. JAMA. 2007Apr.4;297(13):1478–88. Article Link This systematic overview from the excellent JAMA series reviewed the relatively weak evidence regarding assessment of patients with...
by EMOttawa | Aug 22, 2012 | Journal Club, landmark
Journal Club Summary Landmark Series Clark E, Plint AC, Correll R, Gaboury I, Passi B. A Pediatrics. 20 07Mar.1;119(3):460–7. Article Link This high quality RCT by local investigators rigorously compared acetaminophen, ibuprofen and codeine analgesics among...
by EMOttawa | Aug 14, 2012 | Journal Club, landmark
Journal Club Summary Landmark Series Straus SE, Thorpe KE, Holroyd-Leduc J. JAMA. 2006Oct.25;296(16):2012–22. PubMed Link This systematic literature review and meta-analysis in the Rational Clinical Examination series found a non-significant trend towards less...
by emottawa | Aug 7, 2012 | Journal Club
Journal Club Summary Landmark Series Andrew K Chang, Polly E Bijur, Robert H Meyer, Mark K Kenny, Clemencia Solorzano, and E John Gallagher PubMed Link This U.S. randomized trial in ED adults with severe pain found similar effectiveness for intravenous...
by EMOttawa | Jul 31, 2012 | Journal Club, landmark
Journal Club Summary Landmark Series Levitan RM, Kinkle WC, Levin WJ, Everett WW. Ann Emerg Med. 2006 Jun.;47(6):548–55. PubMed Link This U.S. study evaluated manipulation techniques for direct laryngoscopy during endotracheal intubation in 1,530 comparisons performed...
