by Hans Rosenberg | Jan 15, 2018 | Cardiology, Journal Club, landmark
Journal Club Summary Hofmann R, et al. N Engl J Med. 2017 Sep 28;377(13):1240-1249. Methodology Score: 4/5 Usefulness Score: 4/5 Question and Methods: This large, registry-based RCT evaluated the effect of oxygen on patient-centered clinical outcomes...
by Jeff Perry, Shahbaz Syed | Nov 13, 2017 | Commentary, Featured, Infographics, Journal Club, landmark
Dr. Perry and Colleagues have previously derived and validated the Ottawa SAH rule for patients with suspected subarachnoid hemorrhage, here we present the multicenter prospective validation of the rule1, with some insight on the rule from Dr. Perry himself! Note that...
by Hans Rosenberg | Oct 23, 2017 | Journal Club, landmark, Thrombosis
Journal Club Summary Reference: Van der Hulle T, et al. Lancet. 2017 Jul 15;390(10091):289-297. Methodology Score: 4/5 Usefulness Score: 3.5/5 Questions and Methods: This multicenter trial implemented the YEARS simplified algorithm for suspected PE...
by EMOttawa | Jun 19, 2017 | Journal Club, landmark
Journal Club Summary Methodology Score: 4/5 Usefulness Score: 4.5/5 D’Onofrio G, et al JAMA. 2015 Apr 28;313(16):1636-44. Full Article This single, urban center RCT including 329 patients showed that buprenorphine initiated in the ED was more likely to increase...
by EMOttawa | May 15, 2017 | Journal Club, landmark
Journal Club Summary Methodology Score: 3/5 Usefulness Score: 3.5/5 Nijssen EC, et al Lancet. 2017 Feb 20. [Epub ahead of print] Abstract Link This prospective, open-label, single centre, randomized trial of 660 patients found no hydration...
by EMOttawa | Aug 26, 2014 | Journal Club, landmark
Journal Club Summary Methodology Score: 4.5/5 Usefulness Score: 4.5/5 Imazio M, et al. ICAP Investigators. N Engl J Med. 2013 Oct 17;369(16):1522-8. Article Link This multicentre double-blind RCT found that a 3 month course of low-dose...
by EMOttawa | Jan 6, 2014 | Journal Club, landmark
Journal Club Summary Landmark Series Methodology Score: 4/5 Usefulness Score: 4/5 De Backer D, Biston P, Devriendt J, Madl C, Chochrad D, Aldecoa C, Brasseur A, Defrance P, Gottignies P, Vincent JL; SOAP II Investigators. N Engl J Med. 2010 Mar...
by EMOttawa | Nov 18, 2013 | Journal Club, landmark
Journal Club Summary Landmark Series Methodology Score: 4/5 Usefulness Score: 4.5/5 Perner A, et al.; 6S Trial Group; Scandinavian Critical Care Trials Group. N Engl J Med. 2012 Jul 12;367(2):124-34 Article Link This multi-centre, double-blind,...
by EMOttawa | Oct 28, 2013 | Journal Club, landmark
Journal Club Summary Landmark Series Methodology Score: 3.5/5 Usefulness Score: 4/5 Villanueva C, Colomo A, Bosch A, Concepción M, Hernandez-Gea V, Aracil C, Graupera I, Poca M, Alvarez-Urturi C, Gordillo J, Guarner-Argente C, Santaló M, Muñiz E,...
by EMOttawa | Sep 3, 2013 | Journal Club, landmark
Journal Club Summary Landmark Article Series Methodology Score: 4.5/5 Usefulness Score: 4.5/5 Colman I, Friedman BW, Brown MD, Innes GD, Grafstein E, Roberts TE, Rowe BH. BMJ. 2008 Jun 14;336(7657):1359-61 Article Link In this well performed meta-analysis, a...
