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Signal or Noise? Using Inflammatory Markers Wisely Through a Bayesian Lens

Signal or Noise? Using Inflammatory Markers Wisely Through a Bayesian Lens

by Lucy Karp | Mar 19, 2026 | Featured, Gastroenterology, Grand Round Summaries, Immunology, Infectious Disease, Most Viewed, Ophthalmology, Rheumatology

There seems to be a growing cultural obsession with “inflammation”. Scroll through social media long enough and you’ll find sweeping claims: inflammation is the root of fatigue, weight gain, menstrual cramps, brain fog, and even depression. And alongside this...
Trial of Pregabalin for Acute and Chronic Sciatica

Trial of Pregabalin for Acute and Chronic Sciatica

by Hans Rosenberg | Jul 10, 2019 | Full Article, Journal Club, Neurosurgery, Orthopedics

Journal Club Summary Methodology: 3.5/5 Usefulness: 4/5 Mathieson S, et al. N Engl J Med. 2017 Mar 23;376(12):1111-1120.  Question and Methods: Double blind, randomized control trial comparing pregabalin against placebo for reducing leg pain symptoms at 8 weeks in 209...
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