by Emily Cino, Ian Stiell | May 13, 2026 | Gastroenterology, Journal Club
Efficacy and Safety of Pharmacologic Therapies for Nausea and Emesis in the Emergency Department: A Systematic Review and Bayesian Network Meta-analysis. deSouza IS, et al. Ann Emerg Med. 2025 Dec;86(6):646-658. doi: 10.1016/j.annemergmed.2025.06.009. Methodology:...
by Camille Dagenais | May 7, 2026 | Endocrinology, Featured, Gastroenterology, Grand Round Summaries, Resuscitation
GLP-1 receptor agonists have moved from niche diabetes therapies to some of the most commonly encountered medications in modern clinical practice. Drugs like semaglutide and tirzepatide are reshaping the management of obesity and cardiometabolic disease, with millions...
by Lucy Karp | Mar 19, 2026 | Featured, Gastroenterology, Grand Round Summaries, Immunology, Infectious Disease, Most Viewed, Ophthalmology, Rheumatology
There seems to be a growing cultural obsession with “inflammation”. Scroll through social media long enough and you’ll find sweeping claims: inflammation is the root of fatigue, weight gain, menstrual cramps, brain fog, and even depression. And alongside this...
by Maria Berliant, Hans Rosenberg, Venkatesh Thiruganasambandamoorthy | Dec 1, 2025 | Full Article, Gastroenterology, Journal Club, Toxicology
Methodology: 3.5/5 Usefulness: 4/5 Isbister G, et al. J Hepatol. 2025 Oct;83(4):881-887. doi: 10.1016/j.jhep.2025.05.008. Question and Methods: This multicentre unblinded RCT with 204 patients assessed non-inferiority of a 12-hour NAC protocol for single non-massive...
by Samara Adler, Hans Rosenberg, Krishan Yadav | Sep 29, 2025 | Gastroenterology, Journal Club, Pediatrics
Freedman SB, et al. N Engl J Med. 2025 Jul 17;393(3):255-266. doi: 10.1056/NEJMoa2503596. Methodology: 4.5/5 Usefulness: 4/5 Question and Methods: This multicentre, double-blind randomized superiority trial evaluated the effectiveness of oral ondansetron dispensed at...
by Isabella Menchetti | Sep 18, 2025 | Airway, Anesthesiology, emergency, Gastroenterology
A 60-year-old male with a history of cirrhosis arrives in your ED in extremis; no vital signs, massive hematemesis en route, and a presumptive diagnosis of ruptured esophageal varices. Your team initiates the massive transfusion protocol, secures the airway, and...
by Simranjeet Singh, Hans Rosenberg, Venkatesh Thiruganasambandamoorthy | May 12, 2025 | Gastroenterology, Journal Club, Ultrasound
Methodology: 4/5 Usefulness: 3.5/5 Wilson SJ, et al. Ann Emerg Med. 2024 Mar;83(3):235-246. doi: 10.1016/j.annemergmed.2023.09.005. Questions and Method: To determine the diagnostic accuracy of emergency physician performed point of care ultrasound (POCUS) for acute...
by Kaitlin Endres, Mathieu McKinnon | Jan 18, 2024 | Critical Care, emergency, Featured, Gastroenterology, Grand Round Summaries, Surgery, Thrombosis
When working up your patient, how often do you think of problems related to the hepatic venous system? Have you suppressed those memories of time spent over your cadaver in medical school learning the anatomy? By the end of this, you will all be newly discovered...
by Kevin Guo | May 11, 2023 | Endocrinology, Featured, Gastroenterology, Grand Round Summaries, Resuscitation, Surgery
Acute pancreatitis is one of the most common gastroenterology conditions we see in the emergency department with a prevalence of 110-140 cases per 100,000 population. (1) At The Ottawa Hospital alone, we saw over an average of 1 case per day over the last year....
by Kate Holden-Boyd, Hans Rosenberg, Krishan Yadav | Jan 30, 2023 | Critical Care, Featured, Gastroenterology, Journal Club
Methodology: 4/5 Usefulness: 4/5 de-Madaria E, et al. N Engl J Med. 2022 Sep 15;387(11):989-1000. Question and Methods: A multicenter, open-label, randomized control trial assessing the use of aggressive versus moderate fluid resuscitation in acute pancreatitis and...
