Neurosurgery Archives - EMOttawa Blog

Tick. Tock. It’s Time For a TXA Update

by Maeghan Fu, Josee Malette, Pascale King | Mar 11, 2021 | Grand Round Summaries, Hematology, Neurosurgery, Resuscitation, Trauma

Tick. Tock. It’s time for a TXA update. This blog post aims to arm you with the most up-to-date knowledge for the use of tranexamic acid (TXA) in the ED. We will review TXA in the context of gastrointestinal bleeding, traumatic brain injuries, hemoptysis,...

Blunt cerebrovascular injury: The case for universal screening.

by Hans Rosenberg | Jan 11, 2021 | Journal Club, Neurosurgery, Trauma

Methodology: 2/5 Usefulness: 4/5 Leichtle SW, et al. J Trauma Acute Care Surg. 2020 Nov;89(5):880-886. Question and Methods: Existing BCVI screening guidelines misses important injuries; the authors evaluated the diagnostic characteristics of the Modified and...

Prospective Implementation of the Ottawa Subarachnoid Hemorrhage Rule and 6-Hour Computed Tomography Rule

by Hans Rosenberg | Jan 3, 2021 | Full Article, Journal Club, Neurosurgery

Methodology: 4/5 Usefulness: 4/5 Perry JJ, et al. Stroke. 2020 Feb;51(2):424-430. doi: 10.1161/STROKEAHA.119.026969. Question and Methods: Prospective, multi-center before and after study looking at the implementation of the Ottawa Subarachnoid Hemorrhage Rule and...

Subarachnoid Hemorrhage in the ED- What a Headache!

by Michael Hale, Kate O'Connell | Nov 5, 2020 | Featured, Grand Round Summaries, Neurosurgery, Radiology

The diagnosis of subarachnoid hemorrhage (SAH) carries with it remarkable morbidity and mortality. Case fatality rates approach 50% 1,2 Of those who survive, half will experience chronic disability and a significant reduction in health-related quality of...

Effect of Early Sustained Prophylactic Hypothermia on Neurologic Outcomes Among Patients With Severe Traumatic Brain Injury: The POLAR Randomized Clinical Trial.

by Hans Rosenberg | Dec 16, 2019 | Full Article, Journal Club, Neurosurgery, Resuscitation, Trauma

Methodology Score: 3/5 Usefulness Score: 3/5 Cooper DJ, et al. JAMA. 2018;320(21):2211-2220. doi:10.1001/jama.2018.17075 Question/Methods: This study was done to determine the effectiveness of early prophylactic hypothermia compared with normothermic management of...

Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomized, placebo-controlled trial

by Hans Rosenberg | Dec 9, 2019 | Full Article, Neurosurgery, Trauma

Methodology: 3.5/5 Usefulness: 3.5/5 The CRASH-3 trial collaborators. The Lancet. 2019 Oct 14. Online First Editorial: CRASH-3: a win for patients with traumatic brain injury Question and Methods: Multi-centre, randomized, placebo-controlled trial looking at whether...

Trial of Pregabalin for Acute and Chronic Sciatica

by Hans Rosenberg | Jul 10, 2019 | Full Article, Journal Club, Neurosurgery, Orthopedics

Journal Club Summary Methodology: 3.5/5 Usefulness: 4/5 Mathieson S, et al. N Engl J Med. 2017 Mar 23;376(12):1111-1120. Question and Methods: Double blind, randomized control trial comparing pregabalin against placebo for reducing leg pain symptoms at 8 weeks in 209...

Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage (TICH-2): an international randomised, placebo-controlled, phase 3 superiority trial.

by Hans Rosenberg | Mar 18, 2019 | Critical Care, Full Article, Journal Club, landmark, Neurosurgery

Journal Club Methodology Score: 4/5 Usefulness Score: 3/5 Sprigg N, et al. Lancet. 2018 May 26;391(10135):2107-2115 Question and Methods: Multicenter, double-blinded, randomized, placebo-controlled trial comparing if IV TXA vs placebo, given within 8h of spontaneous...