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Journal Club Summary Methodology: 3.5/5 Usefulness: 4/5 Mathieson S, et al. N Engl J Med. 2017 Mar 23;376(12):1111-1120.  Question and Methods: Double blind, randomized control trial comparing pregabalin against placebo for reducing leg pain symptoms at 8 weeks in 209 patients with acute and chronic sciatica. Findings: The authors found a betweenRead More →

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In: Critical Care, Full Article, Journal Club, Neurology, Neurosurgery

Journal Club Methodology Score: 4/5 Usefulness Score: 3/5 Sprigg N, et al. Lancet. 2018 May 26;391(10135):2107-2115 Question and Methods: Multicenter, double-blinded, randomized, placebo-controlled trial comparing if IV TXA vs placebo, given within 8h of spontaneous (non-traumatic) ICH onset, decreased death or dependence at 90 days. Findings: No difference in 90dRead More →