by Camille Dagenais | Apr 23, 2026 | Critical Care, Featured, Grand Round Summaries, Neurology, Neurosurgery, Resuscitation, Trauma
Traumatic brain injury (TBI) is a common yet challenging presentation in emergency medicine. As CT imaging becomes increasingly sensitive, clinicians are identifying more subtle intracranial injuries. The Brain Injury Guidelines (BIG) and Modified Brain Injury...
by Alie Wudwud | Jun 12, 2025 | Critical Care, Featured, Grand Round Summaries, Neurosurgery, Surgery, Trauma
Blunt cerebrovascular injury (BCVI) involves vessel injuries that occur from trauma mechanisms commonly seen in the emergency department: falls down stairs, motor vehicle collisions, and facial trauma. By identifying high-risk patients early, we can decrease the risk...
by Megan Brenkel, Hans Rosenberg, Venkatesh Thiruganasambandamoorthy | May 5, 2025 | Critical Care, Featured, Journal Club, Neurosurgery
Methodology: 4/5 Usefulness: 3/5 English SW, et al. N Engl J Med. 2025 Mar 13;392(11):1079-1088. doi: 10.1056/NEJMoa2410962. Question and Methods: This multicenter RCT assessed whether a liberal (Hgb≤100 g/L) versus restrictive (Hgb≤80 g/L) transfusion strategy...
by Alie Wudwud, Hans Rosenberg, Christian Vaillancourt | Mar 24, 2025 | Featured, Journal Club, Neurosurgery, Trauma
Methodology: 3.5/5 Usefulness: 4/5 Taccone FS, et al. JAMA. 2024 Nov 19;332(19):1623-1633. Question and Methods: This multicenter, randomized trial aimed to determine the optimal hemoglobin transfusion threshold in patients with acute brain injury, comparing a...
by Courtney Price, Hans Rosenberg, Krishan Yadav | Jan 27, 2025 | Full Article, Journal Club, Neurology, Neurosurgery, Thrombosis
Methodology 3/5 Usefulness 3/5 Connolly SJ, et al. N Engl J Med. 2024 May 16;390(19):1745-1755. Editorial: Reversing Oral Anticoagulation in Intracerebral Hemorrhage. Question and Methods: This unblinded, multicentre randomized controlled trial studied whether...
by Heather Moffatt, Hans Rosenberg, Venkatesh Thiruganasambandamoorthy | Nov 29, 2024 | Full Article, Geriatrics, Journal Club, Neurosurgery, Trauma
Methodology: 3.5/5 Usefulness: 3.5/5 CMAJ. 2023 Dec 3;195(47):E1614-E1621. de Wit K, et al. doi: 10.1503/cmaj.230634. Question and Methods: The Falls Decision Rule was derived to identify older adults with fall who do not require CT to rule out intracranial bleeding,...
by Emma Ferguson, Lucy Karp | Sep 1, 2022 | Featured, Neurology, Neurosurgery
Acute stroke care is integrated into emergency medicine in many emergency departments across Canada. Whether you are involved in acute stroke care through consultation with neurology or through tele-stroke, understanding the complications of acute stroke therapy and...
by Renee Bradley, Hans Rosenberg, Jeff Perry | May 2, 2022 | Critical Care, Journal Club, Neurology, Neurosurgery
Methodology: 4.5/5 Usefulness: 4/5 Post R, et al. Lancet. 2021 Jan 9;397(10269):112-118. doi: 10.1016/S0140-6736(20)32518-6. Question and Methods: This prospective, multicentre, randomized, controlled, open-label trial investigated whether administering TXA...
by Graham Wilson, Jeff Perry, Hans Rosenberg | Apr 4, 2022 | Full Article, Journal Club, Neurosurgery, Thrombosis, Trauma
Methodology: 3/5 Usefulness: 3/5 Grewal K, et al. CMAJ. 2021 Oct 12;193(40):E1561-E1567. Question and Methods: Retrospective cohort study evaluating risk of ICH post head injury in ED patients >65 years on warfarin or DOAC or no anticoagulant. Findings: Patients...
by Maeghan Fu, Josee Malette, Pascale King | Mar 11, 2021 | Grand Round Summaries, Hematology, Neurosurgery, Resuscitation, Trauma
Tick. Tock. It’s time for a TXA update. This blog post aims to arm you with the most up-to-date knowledge for the use of tranexamic acid (TXA) in the ED. We will review TXA in the context of gastrointestinal bleeding, traumatic brain injuries, hemoptysis,...
