by Naman Arora | Oct 1, 2026 | Critical Care, Featured, Grand Round Summaries, Infectious Disease, Resuscitation
Sepsis resuscitation has evolved considerably over the past two decades, moving away from rigid protocols toward more individualized care. Yet many familiar targets remain: 30 mL/kg of fluid, a MAP of 65, and lactate clearance. But not every patient benefits from more...
by Mathieu McKinnon | Mar 26, 2026 | Anesthesiology, Critical Care, Featured, Grand Round Summaries, Resuscitation, Trauma
Blood pressure management in trauma is one of the most deceptively complex decisions we make in the emergency department. In the first hour of resuscitation, competing physiologic priorities collide: permissive hypotension may protect clot integrity in hemorrhagic...
by EMOttawa | Jan 6, 2014 | Journal Club, landmark
Journal Club Summary Landmark Series Methodology Score: 4/5 Usefulness Score: 4/5 De Backer D, Biston P, Devriendt J, Madl C, Chochrad D, Aldecoa C, Brasseur A, Defrance P, Gottignies P, Vincent JL; SOAP II Investigators. N Engl J Med. 2010 Mar...
by EMOttawa | Oct 23, 2012 | Journal Club, landmark
Journal Club Summary Methodology Score: 3.5/5 Usefulness Score: 4/5 De Backer D, Aldecoa C, Njimi H, Vincent JL. Crit Care Med. 2012 Mar;40(3):725-30. Article Link This meta-analysis of 6 trials found that in patients with septic shock, dopamine administration was...
